TY - GEN
T1 - Comparison of relative pressures calculated from PC-MRI and SPIV with catheter-based pressure measurements in a stenotic phantom model
AU - Khodarahmil, Iman
AU - Shakeri, Mostafa
AU - Kotys-Traughber, Melanie
AU - Sharp, Michael K.
AU - Amini, Amir A.
PY - 2012
Y1 - 2012
N2 - This paper describes an experimental system for validation of an approach to non-invasive determination of pressure gradients in stenotic flows as encountered in peripheral arterial disease. Pressure gradient across a Gaussian-shaped 87% area stenosis phantom was estimated by solving the pressure Poisson equation (PPE) for a steady flow mimicking the blood flow through the human iliac artery. The velocity field needed to solve the pressure equation was obtained using Phase-Contrast MRI (PC-MRI) and Stereoscopic Particle Image Velocimetry (SPIV). Steady flow rate of 46.9 ml/s was used, which corresponds to a Reynolds number of 188 and 595 at the inlet and stenosis throat, respectively (in the range of mean Reynolds number encountered, in-vivo). Results of PC-MRI and SPIV have been compared to the pressures measured directly by a pressure catheter transducer. The reconstructed pressure drop along the centerline overestimates the catheter reference pressure drop by 8.5% and 10.5% for PC-MRI and SPIV methods, respectively.
AB - This paper describes an experimental system for validation of an approach to non-invasive determination of pressure gradients in stenotic flows as encountered in peripheral arterial disease. Pressure gradient across a Gaussian-shaped 87% area stenosis phantom was estimated by solving the pressure Poisson equation (PPE) for a steady flow mimicking the blood flow through the human iliac artery. The velocity field needed to solve the pressure equation was obtained using Phase-Contrast MRI (PC-MRI) and Stereoscopic Particle Image Velocimetry (SPIV). Steady flow rate of 46.9 ml/s was used, which corresponds to a Reynolds number of 188 and 595 at the inlet and stenosis throat, respectively (in the range of mean Reynolds number encountered, in-vivo). Results of PC-MRI and SPIV have been compared to the pressures measured directly by a pressure catheter transducer. The reconstructed pressure drop along the centerline overestimates the catheter reference pressure drop by 8.5% and 10.5% for PC-MRI and SPIV methods, respectively.
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U2 - 10.1117/12.914716
DO - 10.1117/12.914716
M3 - Conference contribution
AN - SCOPUS:84860726732
SN - 9780819489661
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Medical Imaging 2012
T2 - Medical Imaging 2012: Biomedical Applications in Molecular, Structural, and Functional Imaging
Y2 - 5 February 2012 through 7 February 2012
ER -
