Composite SISCOM perfusion patterns in right and left temporal seizures

R. Edward Hogan, Kitti Kaiboriboon, Mary E. Bertrand, Venkat Rao, Jayant Acharya

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Objective: To compare composite subtraction ictal single-photon emission computed tomography coregistered to magnetic resonance imaging (also known as SISCOM) patterns between right and left medial temporal-onset seizures to document neuroanatomical involvement in perfusion patterns. Design: A retrospective comparative survey. Setting: Epilepsy monitoring unit in a tertiary care referral center. Participants: Subjects with temporal lobe epilepsy (TLE) who underwent ictal single-photon emission computed tomography studies. Main Outcome Measures: Comparison of ictal perfusion pattern changes in subjects with right and left temporal seizures. Results: Composite subtraction ictal single-photon emission computed tomography coregistered to magnetic resonance images showed similar regions of hyperperfusion change in the ipsilateral anteromedial temporal-corpus striatum-insula region in both groups. In the midbrain reticular formation, there was a significant difference in hyperperfusion between the left and rightTLEgroups. In addition, the right, but not the left, TLE group shows contralateral hypoperfusion of the temporoparietal junction. Conclusions: While anteromedial temporal-corpus striatum-insula perfusion patterns are similar, there are brainstem and hemispheric perfusion pattern differences in right and left TLE seizures, confirming pathophysiological differences between the groups. These findings help define neuronal network involvement in TLE seizures, and may explain the differences in clinical symptoms of right and left TLE seizures.

Original languageEnglish (US)
Pages (from-to)1419-1426
Number of pages8
JournalArchives of Neurology
Volume63
Issue number10
DOIs
StatePublished - Oct 17 2006

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Temporal Lobe Epilepsy
Seizures
Perfusion
Single-Photon Emission-Computed Tomography
Stroke
Corpus Striatum
Tertiary Care Centers
Brain Stem
Epilepsy
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Outcome Assessment (Health Care)
Computed Tomography

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Cite this

Hogan, R. Edward ; Kaiboriboon, Kitti ; Bertrand, Mary E. ; Rao, Venkat ; Acharya, Jayant. / Composite SISCOM perfusion patterns in right and left temporal seizures. In: Archives of Neurology. 2006 ; Vol. 63, No. 10. pp. 1419-1426.
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Composite SISCOM perfusion patterns in right and left temporal seizures. / Hogan, R. Edward; Kaiboriboon, Kitti; Bertrand, Mary E.; Rao, Venkat; Acharya, Jayant.

In: Archives of Neurology, Vol. 63, No. 10, 17.10.2006, p. 1419-1426.

Research output: Contribution to journalArticle

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