Comprehensive two-dimensional gas chromatography in forensic science: A critical review of recent trends

B. Gruber, B. A. Weggler, R. Jaramillo, K. A. Murrell, P. K. Piotrowski, Franklin Lewis Dorman, Jr.

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

Comprehensive two-dimensional gas chromatography (GC × GC) has become accepted as one of the most powerful separation techniques in several application areas. In forensic investigations, however, it has not yet been entirely established due to limitations regarding standardized methodology, data interpretation and consistency of results. Nevertheless, GC × GC allows for target analysis, compound class analysis and chemical fingerprinting of samples and is therefore increasingly applied in forensic analytics. In this review, recent and significant advances in GC × GC for application to forensic studies including human scent, arson investigations, security-relevant substances and environmental forensics are discussed. The discussion includes a brief overview of the latest trends and evolutions with regard to the various forensic applications and data evaluation as well as limitations. This leads to the conclusion that the full potential of the comprehensive data sets can only be achieved by implementing standardized analysis and data processing methods.

Original languageEnglish (US)
Pages (from-to)292-301
Number of pages10
JournalTrAC - Trends in Analytical Chemistry
Volume105
DOIs
StatePublished - Aug 1 2018

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Gas chromatography
Forensic science

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Spectroscopy

Cite this

Gruber, B., Weggler, B. A., Jaramillo, R., Murrell, K. A., Piotrowski, P. K., & Dorman, Jr., F. L. (2018). Comprehensive two-dimensional gas chromatography in forensic science: A critical review of recent trends. TrAC - Trends in Analytical Chemistry, 105, 292-301. https://doi.org/10.1016/j.trac.2018.05.017
Gruber, B. ; Weggler, B. A. ; Jaramillo, R. ; Murrell, K. A. ; Piotrowski, P. K. ; Dorman, Jr., Franklin Lewis. / Comprehensive two-dimensional gas chromatography in forensic science : A critical review of recent trends. In: TrAC - Trends in Analytical Chemistry. 2018 ; Vol. 105. pp. 292-301.
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Comprehensive two-dimensional gas chromatography in forensic science : A critical review of recent trends. / Gruber, B.; Weggler, B. A.; Jaramillo, R.; Murrell, K. A.; Piotrowski, P. K.; Dorman, Jr., Franklin Lewis.

In: TrAC - Trends in Analytical Chemistry, Vol. 105, 01.08.2018, p. 292-301.

Research output: Contribution to journalReview article

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AU - Jaramillo, R.

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