Computer-assisted endoscopic coronary artery bypass anastomoses: A chronic animal study

Edward Stephenson, Christopher T. Ducko, Sachin Sankholkar, Eric M. Hoenicke, G. Allen Prophet, Ralph J. Damiano

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Background. With traditional instruments, endoscopic coronary artery bypass grafting (ECABG) has not been possible. This study was designed to determine the feasibility of using a robotically-assisted microsurgical system to perform ECABG in a chronic animal model. Methods. Nine calves were placed on cardiopulmonary bypass after harvesting the left internal mammary artery (LIMA). Subxiphoid endoscopic ports (2 instrument, 1 camera) were placed, and a robotic system was used to perform ECABG between the LIMA and left anterior descending coronary artery. LIMA graft flow (LIMA(Q)) was measured. Animals were sacrificed at 1 month, and hearts underwent angiographic and histologic analyses. Results. Acute graft patency was 89% (8/9). Two animals died suddenly within the first 48 hours. There was no significant difference in mean acute and chronic (n = 6) LIMA(Q) (40.9 ± 4.7 and 38.5 ± 5.0 ml/min, respectively). Survivors had an angiographic patency rate of 100% (6/6), confirmed by histology. Conclusions. This study shows that ECABG is feasible in a chronic animal model with excellent results.

Original languageEnglish (US)
Pages (from-to)838-843
Number of pages6
JournalAnnals of Thoracic Surgery
Volume68
Issue number3
DOIs
StatePublished - Sep 1 1999

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Mammary Arteries
Coronary Artery Bypass
Animal Models
Transplants
Robotics
Cardiopulmonary Bypass
Coronary Vessels
Histology

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Stephenson, E., Ducko, C. T., Sankholkar, S., Hoenicke, E. M., Prophet, G. A., & Damiano, R. J. (1999). Computer-assisted endoscopic coronary artery bypass anastomoses: A chronic animal study. Annals of Thoracic Surgery, 68(3), 838-843. https://doi.org/10.1016/S0003-4975(99)00794-8
Stephenson, Edward ; Ducko, Christopher T. ; Sankholkar, Sachin ; Hoenicke, Eric M. ; Prophet, G. Allen ; Damiano, Ralph J. / Computer-assisted endoscopic coronary artery bypass anastomoses : A chronic animal study. In: Annals of Thoracic Surgery. 1999 ; Vol. 68, No. 3. pp. 838-843.
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Stephenson, E, Ducko, CT, Sankholkar, S, Hoenicke, EM, Prophet, GA & Damiano, RJ 1999, 'Computer-assisted endoscopic coronary artery bypass anastomoses: A chronic animal study', Annals of Thoracic Surgery, vol. 68, no. 3, pp. 838-843. https://doi.org/10.1016/S0003-4975(99)00794-8

Computer-assisted endoscopic coronary artery bypass anastomoses : A chronic animal study. / Stephenson, Edward; Ducko, Christopher T.; Sankholkar, Sachin; Hoenicke, Eric M.; Prophet, G. Allen; Damiano, Ralph J.

In: Annals of Thoracic Surgery, Vol. 68, No. 3, 01.09.1999, p. 838-843.

Research output: Contribution to journalArticle

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AU - Stephenson, Edward

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AU - Damiano, Ralph J.

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N2 - Background. With traditional instruments, endoscopic coronary artery bypass grafting (ECABG) has not been possible. This study was designed to determine the feasibility of using a robotically-assisted microsurgical system to perform ECABG in a chronic animal model. Methods. Nine calves were placed on cardiopulmonary bypass after harvesting the left internal mammary artery (LIMA). Subxiphoid endoscopic ports (2 instrument, 1 camera) were placed, and a robotic system was used to perform ECABG between the LIMA and left anterior descending coronary artery. LIMA graft flow (LIMA(Q)) was measured. Animals were sacrificed at 1 month, and hearts underwent angiographic and histologic analyses. Results. Acute graft patency was 89% (8/9). Two animals died suddenly within the first 48 hours. There was no significant difference in mean acute and chronic (n = 6) LIMA(Q) (40.9 ± 4.7 and 38.5 ± 5.0 ml/min, respectively). Survivors had an angiographic patency rate of 100% (6/6), confirmed by histology. Conclusions. This study shows that ECABG is feasible in a chronic animal model with excellent results.

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