Concentrations of PCB congeners in sera from workers with past and present exposure

M. Luotamo, D. G. Patterson, L. L. Needham, A. Aitio

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12 Scopus citations

Abstract

The isomers indicating occupational exposure to PCB have been identified as 2,4,4′-triCB (IUPAC 28), 2,4,4′,5-tetraCB (IUPAC 74), 2,3,4,4′-tetraCB (IUPAC 60) and 2,3′,4,4′-tetraCB (IUPAC 66)1,2, and those indicating accidental (short term) exposure as 2,4,4′-triCB (IUPAC 28), 2′,3,4-triCB (IUPAC 33) and 2,3′,4,4′-tetraCB (IUPAC 66). The latter isomers also prevailed in continuous exposure in a hazardous waste disposal plant. Abnormal levels of these isomers predicted elevated concentrations of coplanars, non-ortho-chlorinated isomers (IUPAC 77, 81, 126 and 169). Among the non-ortho-chlorobiphenyls 3,3′-4,4′- and 3,4,4′,5-tetraCB concentrations were clearly elevated in exposed groups compared to Finnish referents. 3,4,4′,5-TetraCB levels were below the limit of detection in all referents, elevated concentrations were observed in both capacitor manufacture and hazardous waste disposal. Elevated concentrations of 3,3′,4,4′,5-PentaCB were detected in capacitor manufacture and in some workers in hazardous waste disposal. Elevated concentrations of 3,3′,4,4′,5,5′-hexaCB were observed in capacitor manufacture.

Original languageEnglish (US)
Pages (from-to)171-177
Number of pages7
JournalChemosphere
Volume27
Issue number1-3
DOIs
StatePublished - Jan 1 1993

All Science Journal Classification (ASJC) codes

  • Environmental Engineering
  • Environmental Chemistry
  • Chemistry(all)
  • Pollution
  • Health, Toxicology and Mutagenesis

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