Abstract
Although there have been isolated reports of congestive heart failure (CHF) with normal systolic function, the prevalence and characteristics of this condition have not previously been described. Accordingly, 188 patients with CHF undergoing radionuclide ventriculography were prospectively evaluated. Sixty-seven (36%) had a normal ejection fraction (EF) of 0.45 or greater, and 121, an abnormal EF of less than 0.45. Of these, 72 (55 with an abnormal EF [group I] and 17 with a normal EF [group II]) were also reviewed for clinical characteristics. There was no demographic difference between groups, except that systemic hypertension appeared to be a contributing factor in 65% of the patients in group II, compared with 23% of the patients in group I (p <0.002). Echocardiographic left atrial emptying index, reflecting left ventricular compliance, was determined in 72 patients and 14 normal subjects. Left atrial emptying index in normal control subjects was 0.93 ± 0.11 (± standard deviation), compared with 0.41 ± 0.18 in group I and 0.44 ± 0.19 in group II patients (p <0.001 vs control in both groups). Thus, normal systolic function is common among patients with CHF. Diastolic dysfunction, consistent with a noncompliant left ventricle, was found in both CHF groups.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 778-782 |
| Number of pages | 5 |
| Journal | The American Journal of Cardiology |
| Volume | 54 |
| Issue number | 7 |
| DOIs | |
| State | Published - Oct 1 1984 |
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All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine
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Congestive heart failure with normal systolic function. / Dougherty, Anne Hamilton; Naccarelli, Gerald; Gray, Elayne L.; Hicks, Charles H.; Goldstein, Richard A.
In: The American Journal of Cardiology, Vol. 54, No. 7, 01.10.1984, p. 778-782.Research output: Contribution to journal › Article
TY - JOUR
T1 - Congestive heart failure with normal systolic function
AU - Dougherty, Anne Hamilton
AU - Naccarelli, Gerald
AU - Gray, Elayne L.
AU - Hicks, Charles H.
AU - Goldstein, Richard A.
PY - 1984/10/1
Y1 - 1984/10/1
N2 - Although there have been isolated reports of congestive heart failure (CHF) with normal systolic function, the prevalence and characteristics of this condition have not previously been described. Accordingly, 188 patients with CHF undergoing radionuclide ventriculography were prospectively evaluated. Sixty-seven (36%) had a normal ejection fraction (EF) of 0.45 or greater, and 121, an abnormal EF of less than 0.45. Of these, 72 (55 with an abnormal EF [group I] and 17 with a normal EF [group II]) were also reviewed for clinical characteristics. There was no demographic difference between groups, except that systemic hypertension appeared to be a contributing factor in 65% of the patients in group II, compared with 23% of the patients in group I (p <0.002). Echocardiographic left atrial emptying index, reflecting left ventricular compliance, was determined in 72 patients and 14 normal subjects. Left atrial emptying index in normal control subjects was 0.93 ± 0.11 (± standard deviation), compared with 0.41 ± 0.18 in group I and 0.44 ± 0.19 in group II patients (p <0.001 vs control in both groups). Thus, normal systolic function is common among patients with CHF. Diastolic dysfunction, consistent with a noncompliant left ventricle, was found in both CHF groups.
AB - Although there have been isolated reports of congestive heart failure (CHF) with normal systolic function, the prevalence and characteristics of this condition have not previously been described. Accordingly, 188 patients with CHF undergoing radionuclide ventriculography were prospectively evaluated. Sixty-seven (36%) had a normal ejection fraction (EF) of 0.45 or greater, and 121, an abnormal EF of less than 0.45. Of these, 72 (55 with an abnormal EF [group I] and 17 with a normal EF [group II]) were also reviewed for clinical characteristics. There was no demographic difference between groups, except that systemic hypertension appeared to be a contributing factor in 65% of the patients in group II, compared with 23% of the patients in group I (p <0.002). Echocardiographic left atrial emptying index, reflecting left ventricular compliance, was determined in 72 patients and 14 normal subjects. Left atrial emptying index in normal control subjects was 0.93 ± 0.11 (± standard deviation), compared with 0.41 ± 0.18 in group I and 0.44 ± 0.19 in group II patients (p <0.001 vs control in both groups). Thus, normal systolic function is common among patients with CHF. Diastolic dysfunction, consistent with a noncompliant left ventricle, was found in both CHF groups.
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UR - http://www.scopus.com/inward/citedby.url?scp=0021165442&partnerID=8YFLogxK
U2 - 10.1016/S0002-9149(84)80207-6
DO - 10.1016/S0002-9149(84)80207-6
M3 - Article
C2 - 6486027
AN - SCOPUS:0021165442
VL - 54
SP - 778
EP - 782
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 7
ER -