Consecutive carbon-carbon bond formation via the π-allylpalladium variant of the Heck reaction

Christine S. Nylund, John M. Klopp, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Two CC bonds are readily formed by nucleophilic addition of stabilized carbanions to the π-allylpalladium intermediate regioselectively produced by the Heck reaction of a vinyl bromide and an unactivated olefin. An intramolecular version of this condensation gives functionalized carbobicyclic compounds as products.

Original languageEnglish (US)
Pages (from-to)4287-4290
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number25
DOIs
StatePublished - Jun 20 1994

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Consecutive carbon-carbon bond formation via the π-allylpalladium variant of the Heck reaction'. Together they form a unique fingerprint.

Cite this