Contact urticaria and allergic contact dermatitis to benzocaine gel

Michael E. Ryan, Lieutenant Colonel, Brian M. Davis, James G. Marks

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


A 39-year-old man developed edema and vesiculation of the oral mucosa following the application of benzocaine (Hurricaine) gel. Open testing demonstrated an immediate urticarial reaction. Closed patch tests were positive after 48 hours. The contact dermatitis was consistent with a delayed-type hypersensitivity. It appears, however, that a nonimmunologic mechanism caused the contact urticaria since passive transfer was negative.

Original languageEnglish (US)
Pages (from-to)221-223
Number of pages3
JournalJournal of the American Academy of Dermatology
Issue number3
StatePublished - 1980

All Science Journal Classification (ASJC) codes

  • Dermatology


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