Control of interferences in the analysis of human adipose tissue to 2,3,7,8‐tetrachlorodibenzo‐p dioxin (TCDD)

D. G. Patterson, J. S. Holler, D. F. Groce, L. R. Alexander, C. R. Lapeza, R. C. O'Connor, J. A. Liddle

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Abstract

While developing a method to analyze human adipose tissue for 2,3,7,8‐tetrachloro‐dibenzo‐p‐dioxin (TCDD) at the 1 ppt level, we observed several peaks with all of the analytical characteristics of TCDDs in the analyses of wipe tests and blank, quality control, and human adipose samples at concentrations equal to the low part‐per‐trillion level in a 10 g sample. The source of these contaminants was established to be a cleaning solution used to wash the floors in the laboratory performing the analysis.

Original languageEnglish (US)
Pages (from-to)355-360
Number of pages6
JournalEnvironmental Toxicology and Chemistry
Volume5
Issue number4
DOIs
Publication statusPublished - Apr 1986

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All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Health, Toxicology and Mutagenesis

Cite this

Patterson, D. G., Holler, J. S., Groce, D. F., Alexander, L. R., Lapeza, C. R., O'Connor, R. C., & Liddle, J. A. (1986). Control of interferences in the analysis of human adipose tissue to 2,3,7,8‐tetrachlorodibenzo‐p dioxin (TCDD). Environmental Toxicology and Chemistry, 5(4), 355-360. https://doi.org/10.1002/etc.5620050404