Control of traveling waves in the mammalian cortex

Kristen A. Richardson; Steven J. Schiff; Bruce J. Gluckman

doi:10.1103/PhysRevLett.94.028103

Control of traveling waves in the mammalian cortex

Kristen A. Richardson, Steven J. Schiff, Bruce J. Gluckman

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Abstract

We experimentally confirmed predictions that modulation of the neuronal threshold with electrical fields can speed up, slow down, and even block traveling waves in neocortical slices. The predictions are based on a Wilson-Cowan-type integro-differential equation model of propagating neocortical activity. Wave propagation could be modified quickly and reversibly within targeted regions of the network. To the best of our knowledge, this is the first example of direct modulation of the threshold to control wave propagation in a neural system.

Original language	English (US)
Article number	028103
Journal	Physical review letters
Volume	94
Issue number	2
DOIs	https://doi.org/10.1103/PhysRevLett.94.028103
State	Published - Jan 21 2005

All Science Journal Classification (ASJC) codes

Physics and Astronomy(all)

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10.1103/PhysRevLett.94.028103

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