Controlled ovarian hyperstimulation and intrauterine insemination for treatment of infertility

William Dodson, A. F. Haney

Research output: Contribution to journalReview article

209 Citations (Scopus)

Abstract

Empirical therapy for subfertility using assisted reproductive technologies recently has gained popularity; however, the cost-effectiveness of these therapies, compared with an untreated control group, has not been established. Similarly, there has been no comparative cost analysis of the utility of controlled ovarian hyperstimulation and IUI in the management of the same condition. Significant PRs in untreated couples with subfertility mandate the design and execution of controlled trials to ascertain the role of controlled ovarian hyperstimulation and IUI in infertility therapy. Various disorders of subfertility have been treated with controlled ovarian hyperstimulation and IUI. The rationale for this therapy is the increase in gamete density at the site of fertilization, as with GIFT and IVF when used for management of the same problems. The live birth rate per initiated cycle and risk of complications are similar to results recently reported for GIFT and IVF. The utility of controlled ovarian hyperstimulation and IUI still remains controversial. When the relatively low direct and indirect costs of controlled ovarian hyperstimulation and IUI are considered, acknowledging the lack of prospective, controlled studies this procedure appears to be at least as cost-effective as GIFT and IVF.

Original languageEnglish (US)
Pages (from-to)457-467
Number of pages11
JournalFertility and Sterility
Volume55
Issue number3
DOIs
StatePublished - Jan 1 1991

Fingerprint

Insemination
Infertility
Cost-Benefit Analysis
Costs and Cost Analysis
Assisted Reproductive Techniques
Birth Rate
Live Birth
Therapeutics
Fertilization
Germ Cells
Prospective Studies
Control Groups

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this

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Controlled ovarian hyperstimulation and intrauterine insemination for treatment of infertility. / Dodson, William; Haney, A. F.

In: Fertility and Sterility, Vol. 55, No. 3, 01.01.1991, p. 457-467.

Research output: Contribution to journalReview article

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