CuI-catalysed coupling of arylboronate esters with aryl and heteroaryl iodides and bromides is described. The transformation affords products in good yields using 5-10 mol% catalyst loadings. The described reaction requires a P,N-based bidentate ligand in combination with CuI for aryl-aryl coupling, but it proceeds without external ligands for aryl-heteroaryl coupling to afford the products. The reaction protocol can also be applied to achieve biarylation of diiodoarenes in reasonable yields.
All Science Journal Classification (ASJC) codes
- Organic Chemistry