Covariate adjusted weighted normal spatial scan statistics with applications to study geographic clustering of obesity and lung cancer mortality in the United States

Lan Huang, Ram C. Tiwari, Linda W. Pickle, Zhaohui Zou

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

In the field of cluster detection, a weighted normal model-based scan statistic was recently developed to analyze regional continuous data and to evaluate the clustering pattern of pre-defined cells (such as state, county, tract, school, hospital) that include many individuals. The continuous measures of interest are, for example, the survival rate, mortality rate, length of physical activity, or the obesity measure, namely, body mass index, at the cell level with an uncertainty measure for each cell. In this paper, we extend the method to search for clusters of the cells after adjusting for single/multiple categorical/continuous covariates. We apply the proposed method to 1999-2003 obesity data in the United States (US) collected by CDC's Behavioral Risk Factor Surveillance System with adjustment for age and race, and to 1999-2003 lung cancer age-adjusted mortality data by gender in the United States from the Surveillance Epidemiology and End Results (SEER Program) with adjustment for smoking and income.

Original languageEnglish (US)
Pages (from-to)2410-2422
Number of pages13
JournalStatistics in Medicine
Volume29
Issue number23
DOIs
StatePublished - Oct 15 2010

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Scan Statistic
Obesity
Lung Cancer
Mortality
Cluster Analysis
Covariates
Lung Neoplasms
Clustering
SEER Program
Cell
Surveillance
Adjustment
Cluster Detection
Behavioral Risk Factor Surveillance System
Uncertainty Measure
Mortality Rate
Smoking
Epidemiology
Risk Factors
Centers for Disease Control and Prevention (U.S.)

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Statistics and Probability

Cite this

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Covariate adjusted weighted normal spatial scan statistics with applications to study geographic clustering of obesity and lung cancer mortality in the United States. / Huang, Lan; Tiwari, Ram C.; Pickle, Linda W.; Zou, Zhaohui.

In: Statistics in Medicine, Vol. 29, No. 23, 15.10.2010, p. 2410-2422.

Research output: Contribution to journalArticle

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