Creation of functional micro/nano systems through top-down and bottom-up approaches

Tak Sing Wong, Branden Brough, Chih Ming Ho

Research output: Contribution to journalReview article

30 Scopus citations

Abstract

Mimicking nature's approach in creating devices with similar functional complexity is one of the ultimate goals of scientists and engineers. The remarkable elegance of these naturally evolved structures originates from bottom-up self-assembly processes. The seamless integration of top-down fabrication and bottom-up synthesis is the challenge for achieving intricate artificial systems. In this paper, technologies necessary for guided bottom-up assembly such as molecular manipulation, molecular binding, and the self assembling of molecules will be reviewed. In addition, the current progress of synthesizing mechanical devices through top-down and bottom-up approaches will be discussed.

Original languageEnglish (US)
Pages (from-to)1-55
Number of pages55
JournalMCB Molecular and Cellular Biomechanics
Volume6
Issue number1
StatePublished - May 22 2009

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Molecular Medicine
  • Molecular Biology
  • Cell Biology

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