Criteria for annotation of plant microRNAs

Blake C. Meyers, Michael J. Axtell, Bonnie Bartel, David P. Bartel, David Baulcombe, John L. Bowman, Xiaofeng Cao, James C. Carrington, Xuemei Chen, Pamela J. Green, Sam Griffiths-Jones, Steven E. Jacobsen, Allison C. Mallory, Robert A. Martienssen, R. Scott Poethig, Yijun Qi, Herve Vaucheret, Olivier Voinnet, Yuichiro Watanabe, Detlef WeigelJian Kang Zhui

Research output: Contribution to journalComment/debate

888 Scopus citations

Abstract

MicroRNAs (miRNAs) are ∼21 nucleotide noncoding RNAs produced by Dicer-catalyzed excision from stem-loop precursors. Many plant miRNAs play critical roles in development, nutrient homeostasis, abiotic stress responses, and pathogen responses via interactions with specific target mRNAs. miRNAs are not the only Dicer-derived small RNAs produced by plants: A substantial amount of the total small RNA abundance and an overwhelming amount of small RNA sequence diversity is contributed by distinct classes of 21- to 24-nucleotide short interfering RNAs. This fact, coupled with the rapidly increasing rate of plant small RNA discovery, demands an increased rigor in miRNA annotations. Herein, we update the specific criteria required for the annotation of plant miRNAs, including experimental and computational data, as well as refinements to standard nomenclature.

Original languageEnglish (US)
Pages (from-to)3186-3190
Number of pages5
JournalPlant Cell
Volume20
Issue number12
DOIs
StatePublished - Dec 2008

All Science Journal Classification (ASJC) codes

  • Plant Science
  • Cell Biology

Fingerprint Dive into the research topics of 'Criteria for annotation of plant microRNAs'. Together they form a unique fingerprint.

  • Cite this

    Meyers, B. C., Axtell, M. J., Bartel, B., Bartel, D. P., Baulcombe, D., Bowman, J. L., Cao, X., Carrington, J. C., Chen, X., Green, P. J., Griffiths-Jones, S., Jacobsen, S. E., Mallory, A. C., Martienssen, R. A., Poethig, R. S., Qi, Y., Vaucheret, H., Voinnet, O., Watanabe, Y., ... Zhui, J. K. (2008). Criteria for annotation of plant microRNAs. Plant Cell, 20(12), 3186-3190. https://doi.org/10.1105/tpc.108.064311