Current status of pediatric/neonatal extracorporeal life support: Clinical outcomes, circuit evolution, and translational research

Rahul Vasavada, Feng Qiu, Akif Undar

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Extracorporeal life support (ECLS) offers lifesaving mechanical circulatory support for patients afflicted with respiratory and/or cardiac failure. Neonatal respiratory patients have higher survival rates compared to pediatric patients, while, for cardiac cases, pediatric patients are more likely to survive. The indications for ECLS have been expanded due to the improved technology and favorable outcomes. However, the rate of mortality and morbidity for ECLS patients remains significant. Mechanical complications still comprise a large percentage of ECLS complications, leaving definite room for improvement in ECLS circuit technology in the future. As a pre-clinical evaluating tool, translational research will provide more useful information for the selection of ECLS devices, encourage further development of ECLS technology, and, ultimately, benefit the patients.

Original languageEnglish (US)
Pages (from-to)294-301
Number of pages8
JournalPerfusion
Volume26
Issue number4
DOIs
StatePublished - Jul 2011

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Safety Research
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing

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