Data assimilation of glucose dynamics for use in the intensive care unit

Madineh Sedigh-Sarvestani, David J. Albers, Bruce J. Gluckman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Abstract

We know much about the glucose regulatory system, yet the application of this knowledge is limited because simultaneous measurements of insulin and glucose are difficult to obtain. We present a data assimilation framework for combining sparse measurements of the glucose regulatory system, available in the intensive care unit setting, with a nonlinear computational model to estimate unmeasured variables and unknown parameters. We also demonstrate a method for choosing the best variables for measurement. We anticipate that this framework will improve glucose maintenance therapies and shed light on the underlying biophysical process.

Original languageEnglish (US)
Title of host publication2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012
Pages5437-5440
Number of pages4
DOIs
StatePublished - Dec 14 2012
Event34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012 - San Diego, CA, United States
Duration: Aug 28 2012Sep 1 2012

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Other

Other34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
CountryUnited States
CitySan Diego, CA
Period8/28/129/1/12

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All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Sedigh-Sarvestani, M., Albers, D. J., & Gluckman, B. J. (2012). Data assimilation of glucose dynamics for use in the intensive care unit. In 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012 (pp. 5437-5440). [6347224] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2012.6347224