Delayed puberty.

Edward O. Reiter, Peter Lee

Research output: Contribution to journalReview article

20 Citations (Scopus)

Abstract

Normal puberty is a time of life and a process of development that results in full adult maturity of growth, sexual development, and psychosocial achievement. Delayed puberty describes the clinical condition in which the pubertal events start late (usually > +2.5 SD later than the mean) or are attenuated in progression. The differential diagnosis includes syndromes of low gonadotropin production, usually constitutional delay of growth and maturation associated with chronic disease, but also an array of gene-mediated disorders, and syndromes of primary gonadal dysfunction with hypergonadotropic hypogonadism, including Turner and Klinefelter syndromes, and a group of acquired and genetic abnormalities. Diagnostic assessment and varied therapeutic modalities are discussed. The issues of androgen or estrogen therapy are important to assess, and growth hormone treatment remains a difficult dilemma.

Original languageEnglish (US)
JournalAdolescent medicine (Philadelphia, Pa.)
Volume13
Issue number1
StatePublished - Jan 1 2002

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Delayed Puberty
Klinefelter Syndrome
Sexual Development
Turner Syndrome
Hypogonadism
Puberty
Gonadotropins
Growth and Development
Androgens
Growth Hormone
Estrogens
Differential Diagnosis
Chronic Disease
Therapeutics
Growth
Genes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Reiter, Edward O. ; Lee, Peter. / Delayed puberty. In: Adolescent medicine (Philadelphia, Pa.). 2002 ; Vol. 13, No. 1.
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Delayed puberty. / Reiter, Edward O.; Lee, Peter.

In: Adolescent medicine (Philadelphia, Pa.), Vol. 13, No. 1, 01.01.2002.

Research output: Contribution to journalReview article

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