Mosquito specific viruses such as densonucleosis viruses (‘densoviruses’) have long been suggested as alternative mosquito control agents in the face of increasing insecticide resistance. Densoviruses are very species-specific and have been found to infect many important mosquito species. While some strains are highly pathogenic, other strains are more benign. Densoviruses have been proposed as a way to reduce mosquito populations through pathogenic interactions, but genetic strategies such as viral paratrangenesis offer new approaches. As small single-stranded DNA viruses, densoviruses can be easily genetically modified for the expression of genes or non-coding RNAs. A growing literature and variety of techniques have shown the potential for the use of densoviruses in the control of mosquitoes or mosquito-borne pathogens as well as the usefulness of densoviruses as molecular tools for understanding mosquito biology.
All Science Journal Classification (ASJC) codes
- Ecology, Evolution, Behavior and Systematics
- Insect Science