Depot leuproltde acetate for treatment of precocious puberty

Katrina L. Parker, Peter A. Lee

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Leuprolide acetate (D-Leu 6 des-Gly-NH210, Pro-ethylamide9) for depot suspension has been shown to be effective in suppressing gonadotropins in 6 patients. Serum LH and FSH response to exogenous LHRH was obliterated after 4 weeks and weekly urinary gonadotropin levels during depot therapy were suppressed. This form of this drug should be effective in the treatment of precocious puberty.

Original languageEnglish (US)
Pages (from-to)689-691
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume69
Issue number3
DOIs
StatePublished - Sep 1989

Fingerprint

Precocious Puberty
Gonadotropins
Acetates
Leuprolide
Gonadotropin-Releasing Hormone
Suspensions
Therapeutics
Serum
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

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Depot leuproltde acetate for treatment of precocious puberty. / Parker, Katrina L.; Lee, Peter A.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 69, No. 3, 09.1989, p. 689-691.

Research output: Contribution to journalArticle

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AU - Lee, Peter A.

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AB - Leuprolide acetate (D-Leu 6 des-Gly-NH210, Pro-ethylamide9) for depot suspension has been shown to be effective in suppressing gonadotropins in 6 patients. Serum LH and FSH response to exogenous LHRH was obliterated after 4 weeks and weekly urinary gonadotropin levels during depot therapy were suppressed. This form of this drug should be effective in the treatment of precocious puberty.

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