Depression and pancreatic cancer

Elisabeth Kunkel, Jimmie Holland

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Depression and psychological distress appear to be greater in patients with pancreatic cancer, compared to other equally ill patients with cancer, including those with other abnormal neoplasms. The several hypotheses regarding etiology are unproven, but the possibility of a tumor-related paraneoplastic syndrome which promotes the production of a false neurotransmitter capable of altering mood appears most logical at present. However, patients with pancreatic cancer have tumors with known poor prognosis and they often have pain. Both factors contribute to depression. Management of depression depends upon attention to adequate pain control, use of antidepressants and psychological support. Depression in pancreatic cancer raises challenging questions, both about its cause and treatment. Further research study of its psychological and biological components is important in oncology.

Original languageEnglish (US)
Pages (from-to)194-198
Number of pages5
JournalJournal of Pain and Symptom Management
Volume3
Issue number4
DOIs
StatePublished - Jan 1 1988

Fingerprint

Pancreatic Neoplasms
Depression
Psychology
Neoplasms
Paraneoplastic Syndromes
Pain
Antidepressive Agents
Neurotransmitter Agents
Research
Therapeutics

All Science Journal Classification (ASJC) codes

  • Nursing(all)
  • Clinical Neurology
  • Anesthesiology and Pain Medicine

Cite this

Kunkel, Elisabeth ; Holland, Jimmie. / Depression and pancreatic cancer. In: Journal of Pain and Symptom Management. 1988 ; Vol. 3, No. 4. pp. 194-198.
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Depression and pancreatic cancer. / Kunkel, Elisabeth; Holland, Jimmie.

In: Journal of Pain and Symptom Management, Vol. 3, No. 4, 01.01.1988, p. 194-198.

Research output: Contribution to journalArticle

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