Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction

Hemakesh Mohapatra, Kyle M. Schmid, Scott T. Phillips

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

This Communication describes three small molecule reagents that amplify the signal for a detection event via an autocatalytic reaction. Two signals are obtained from each reagent: (i) the dibenzofulvene chromophore and (ii) piperidine, which can be visualized using a pH indicator dye. The reagents are demonstrated in a model assay for palladium.

Original languageEnglish (US)
Pages (from-to)3018-3020
Number of pages3
JournalChemical Communications
Volume48
Issue number24
DOIs
StatePublished - Feb 22 2012

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint Dive into the research topics of 'Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction'. Together they form a unique fingerprint.

  • Cite this