Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors

Dale L. Boger, Monica J. Kochanny, Hui Cai, Diane Wyatt, Paul A. Kitos, M. S. Warren, J. Ramcharan, Lata T. Gooljarsingh, Stephen J. Benkovic

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

The synthesis and evaluation of 1 4 as potential inhibitors of GAR Tfase and AICAR Tfase are detailed. Copyright (C) 1998 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)643-659
Number of pages17
JournalBioorganic and Medicinal Chemistry
Volume6
Issue number6
DOIs
StatePublished - Jun 1998

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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