Detection and size measurement of individual hemozoin nanocrystals in aquatic environment using a whispering gallery mode resonator

Woosung Kim, Sahin Kaya Ozdemir, Jiangang Zhu, Monifi Faraz, Cevayir Coban, Lan Yang

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

We, for the first time, report the detection and the size measurement of single nanoparticles (i.e. polystyrene) in aquatic environment using mode splitting in a whispering gallery mode (WGM) optical resonator, namely a microtoroid resonator. Using this method we achieved detecting and measuring individual synthetic hemozoin nanocrystals?a hemoglobin degradation by-product of malarial parasites?dispersed in a solution or in air. The results of size measurement in solution and in air agree with each other and with those obtained using scanning electron microscope and dynamic light scattering. Moreover, we compare the sensing capabilities of the degenerate (single resonance) and non-degenerate (split mode, doublet) operation regimes of the WGM resonator.

Original languageEnglish (US)
Pages (from-to)29426-29446
Number of pages21
JournalOptics Express
Volume20
Issue number28
DOIs
StatePublished - Dec 31 2012

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics

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