Determinants of behavioral and psychological symptoms of dementia

A scoping review of the evidence

Ann Marie Kolanowski, Marie P. Boltz, Elizabeth Galik, Laura N. Gitlin, Helen C. Kales, Barbara Resnick, Kimberly Sue Van Haitsma, Amy Knehans, Jane E. Sutterlin, Justine S. Sefcik, Wen Liu, Darina V. Petrovsky, Lauren Massimo, Andrea Gilmore-Bykovskyi, Margaret MacAndrew, Glenna Brewster, Vycki Nalls, Ying-ling Jao, Naomi Duffort, Danny Scerpella

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background Behavioral and psychological symptoms of dementia (BPSD) are prevalent in people with neurodegenerative diseases. Purpose In this scoping review the Kales, Gitlin and Lykestos framework is used to answer the question: What high quality evidence exists for the patient, caregiver and environmental determinants of five specific BPSD: aggression, agitation, apathy, depression and psychosis? Method An a priori review protocol was developed; 692 of 6013 articles retrieved in the search were deemed eligible for review. Gough's Weight of Evidence Framework and the Cochrane Collaboration's tool for assessing risk of bias were used. The findings from 56 high quality/low bias articles are summarized. Discussion Each symptom had its own set of determinants, but many were common across several symptoms: neurodegeneration, type of dementia, severity of cognitive impairments, and declining functional abilities, and to a lesser extent, caregiver burden and communication. Conclusion Research and policy implications are relevant to the National Plan to Address Alzheimer's Disease.

Original languageEnglish (US)
Pages (from-to)515-529
Number of pages15
JournalNursing Outlook
Volume65
Issue number5
DOIs
StatePublished - Sep 1 2017

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Behavioral Symptoms
Dementia
Psychology
Caregivers
Apathy
Aptitude
Brassica
Aggression
Neurodegenerative Diseases
Psychotic Disorders
Alzheimer Disease
Communication
Depression
Weights and Measures
Research

All Science Journal Classification (ASJC) codes

  • Nursing(all)

Cite this

Kolanowski, Ann Marie ; Boltz, Marie P. ; Galik, Elizabeth ; Gitlin, Laura N. ; Kales, Helen C. ; Resnick, Barbara ; Van Haitsma, Kimberly Sue ; Knehans, Amy ; Sutterlin, Jane E. ; Sefcik, Justine S. ; Liu, Wen ; Petrovsky, Darina V. ; Massimo, Lauren ; Gilmore-Bykovskyi, Andrea ; MacAndrew, Margaret ; Brewster, Glenna ; Nalls, Vycki ; Jao, Ying-ling ; Duffort, Naomi ; Scerpella, Danny. / Determinants of behavioral and psychological symptoms of dementia : A scoping review of the evidence. In: Nursing Outlook. 2017 ; Vol. 65, No. 5. pp. 515-529.
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abstract = "Background Behavioral and psychological symptoms of dementia (BPSD) are prevalent in people with neurodegenerative diseases. Purpose In this scoping review the Kales, Gitlin and Lykestos framework is used to answer the question: What high quality evidence exists for the patient, caregiver and environmental determinants of five specific BPSD: aggression, agitation, apathy, depression and psychosis? Method An a priori review protocol was developed; 692 of 6013 articles retrieved in the search were deemed eligible for review. Gough's Weight of Evidence Framework and the Cochrane Collaboration's tool for assessing risk of bias were used. The findings from 56 high quality/low bias articles are summarized. Discussion Each symptom had its own set of determinants, but many were common across several symptoms: neurodegeneration, type of dementia, severity of cognitive impairments, and declining functional abilities, and to a lesser extent, caregiver burden and communication. Conclusion Research and policy implications are relevant to the National Plan to Address Alzheimer's Disease.",
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Kolanowski, AM, Boltz, MP, Galik, E, Gitlin, LN, Kales, HC, Resnick, B, Van Haitsma, KS, Knehans, A, Sutterlin, JE, Sefcik, JS, Liu, W, Petrovsky, DV, Massimo, L, Gilmore-Bykovskyi, A, MacAndrew, M, Brewster, G, Nalls, V, Jao, Y, Duffort, N & Scerpella, D 2017, 'Determinants of behavioral and psychological symptoms of dementia: A scoping review of the evidence', Nursing Outlook, vol. 65, no. 5, pp. 515-529. https://doi.org/10.1016/j.outlook.2017.06.006

Determinants of behavioral and psychological symptoms of dementia : A scoping review of the evidence. / Kolanowski, Ann Marie; Boltz, Marie P.; Galik, Elizabeth; Gitlin, Laura N.; Kales, Helen C.; Resnick, Barbara; Van Haitsma, Kimberly Sue; Knehans, Amy; Sutterlin, Jane E.; Sefcik, Justine S.; Liu, Wen; Petrovsky, Darina V.; Massimo, Lauren; Gilmore-Bykovskyi, Andrea; MacAndrew, Margaret; Brewster, Glenna; Nalls, Vycki; Jao, Ying-ling; Duffort, Naomi; Scerpella, Danny.

In: Nursing Outlook, Vol. 65, No. 5, 01.09.2017, p. 515-529.

Research output: Contribution to journalArticle

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T1 - Determinants of behavioral and psychological symptoms of dementia

T2 - A scoping review of the evidence

AU - Kolanowski, Ann Marie

AU - Boltz, Marie P.

AU - Galik, Elizabeth

AU - Gitlin, Laura N.

AU - Kales, Helen C.

AU - Resnick, Barbara

AU - Van Haitsma, Kimberly Sue

AU - Knehans, Amy

AU - Sutterlin, Jane E.

AU - Sefcik, Justine S.

AU - Liu, Wen

AU - Petrovsky, Darina V.

AU - Massimo, Lauren

AU - Gilmore-Bykovskyi, Andrea

AU - MacAndrew, Margaret

AU - Brewster, Glenna

AU - Nalls, Vycki

AU - Jao, Ying-ling

AU - Duffort, Naomi

AU - Scerpella, Danny

PY - 2017/9/1

Y1 - 2017/9/1

N2 - Background Behavioral and psychological symptoms of dementia (BPSD) are prevalent in people with neurodegenerative diseases. Purpose In this scoping review the Kales, Gitlin and Lykestos framework is used to answer the question: What high quality evidence exists for the patient, caregiver and environmental determinants of five specific BPSD: aggression, agitation, apathy, depression and psychosis? Method An a priori review protocol was developed; 692 of 6013 articles retrieved in the search were deemed eligible for review. Gough's Weight of Evidence Framework and the Cochrane Collaboration's tool for assessing risk of bias were used. The findings from 56 high quality/low bias articles are summarized. Discussion Each symptom had its own set of determinants, but many were common across several symptoms: neurodegeneration, type of dementia, severity of cognitive impairments, and declining functional abilities, and to a lesser extent, caregiver burden and communication. Conclusion Research and policy implications are relevant to the National Plan to Address Alzheimer's Disease.

AB - Background Behavioral and psychological symptoms of dementia (BPSD) are prevalent in people with neurodegenerative diseases. Purpose In this scoping review the Kales, Gitlin and Lykestos framework is used to answer the question: What high quality evidence exists for the patient, caregiver and environmental determinants of five specific BPSD: aggression, agitation, apathy, depression and psychosis? Method An a priori review protocol was developed; 692 of 6013 articles retrieved in the search were deemed eligible for review. Gough's Weight of Evidence Framework and the Cochrane Collaboration's tool for assessing risk of bias were used. The findings from 56 high quality/low bias articles are summarized. Discussion Each symptom had its own set of determinants, but many were common across several symptoms: neurodegeneration, type of dementia, severity of cognitive impairments, and declining functional abilities, and to a lesser extent, caregiver burden and communication. Conclusion Research and policy implications are relevant to the National Plan to Address Alzheimer's Disease.

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