Determination of polycyclic aromatic hydrocarbons in urine by solid phase extraction and GC/HRMS

Wenlin Huang, Christopher J. Smith, Charisse J. Walcott, Zheng Li, Selvin Edwards, Melvin Bullock, James Grainger, Donald George Jr Patterson

Research output: Contribution to conferencePaper

Abstract

The polycyclic aromatic hydrocarbons (PAH) in urine were analyzed using analytic method of solid phase extraction (SPE). The urine samples were spiked with 9 carbon-13 labeled standards which were hydrolyzed by β- glucuronidase/arylsulfatase. The solutions were blown in an evaporator and extracts were reconstituted in toluene. The method detection limits (MDL) ranged from 2 ng/L for 1-hydroxypyrene to 43.5 ng/L for 1-hydroxynaphthalene which produced good specificity, precision, linearity and recovery.

Original languageEnglish (US)
Pages683-684
Number of pages2
Publication statusPublished - Dec 1 2002
EventProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: Jun 2 2002Jun 6 2002

Other

OtherProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
CountryUnited States
CityOrlando, FL
Period6/2/026/6/02

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All Science Journal Classification (ASJC) codes

  • Spectroscopy

Cite this

Huang, W., Smith, C. J., Walcott, C. J., Li, Z., Edwards, S., Bullock, M., ... Patterson, D. G. J. (2002). Determination of polycyclic aromatic hydrocarbons in urine by solid phase extraction and GC/HRMS. 683-684. Paper presented at Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, United States.