Development of a device for measuring adherence of skin grafts to the wound surface

Cheng Dong, E. Mead, R. Skalak, Y. C. Fung, J. C. Debes, R. L. Zapata-Sirvent, C. Andree, G. Greenleaf, M. Cooper, J. F. Hansbrough

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Adherence of a biological graft to the wound surface is the most important factor influencing the ultimate success of graft viability. A machine has been developed to test the adherence of biological graft materials to a substrate such as a wound surface. The peeling mode, which yields reproducible quantitative measurements of adherence, is a standard method for testing adhesives. The device is designed to continuously measure the force required to peel the graft from the substrate at a constant rate. This force is a function of the energy of adhesion per unit area of adhered surface. This device has been used to measure the peeling force of (2×2 cm) skin grafts which are applied to full-thickness wounds on mice. Results of tests on adherence of autografts on mice show that the peeling force increases significantly with time over the first 9 days of healing. Thus, this device is useful in quantitative comparison of various skin grafting techniques and artificial grafts.

Original languageEnglish (US)
Pages (from-to)51-55
Number of pages5
JournalAnnals of Biomedical Engineering
Volume21
Issue number1
DOIs
StatePublished - Jan 1 1993

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Grafts
Skin
Peeling
Substrates
Adhesives
Adhesion
Testing

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

Cite this

Dong, C., Mead, E., Skalak, R., Fung, Y. C., Debes, J. C., Zapata-Sirvent, R. L., ... Hansbrough, J. F. (1993). Development of a device for measuring adherence of skin grafts to the wound surface. Annals of Biomedical Engineering, 21(1), 51-55. https://doi.org/10.1007/BF02368164
Dong, Cheng ; Mead, E. ; Skalak, R. ; Fung, Y. C. ; Debes, J. C. ; Zapata-Sirvent, R. L. ; Andree, C. ; Greenleaf, G. ; Cooper, M. ; Hansbrough, J. F. / Development of a device for measuring adherence of skin grafts to the wound surface. In: Annals of Biomedical Engineering. 1993 ; Vol. 21, No. 1. pp. 51-55.
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Dong, C, Mead, E, Skalak, R, Fung, YC, Debes, JC, Zapata-Sirvent, RL, Andree, C, Greenleaf, G, Cooper, M & Hansbrough, JF 1993, 'Development of a device for measuring adherence of skin grafts to the wound surface', Annals of Biomedical Engineering, vol. 21, no. 1, pp. 51-55. https://doi.org/10.1007/BF02368164

Development of a device for measuring adherence of skin grafts to the wound surface. / Dong, Cheng; Mead, E.; Skalak, R.; Fung, Y. C.; Debes, J. C.; Zapata-Sirvent, R. L.; Andree, C.; Greenleaf, G.; Cooper, M.; Hansbrough, J. F.

In: Annals of Biomedical Engineering, Vol. 21, No. 1, 01.01.1993, p. 51-55.

Research output: Contribution to journalArticle

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AU - Debes, J. C.

AU - Zapata-Sirvent, R. L.

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AU - Cooper, M.

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