Development of a wavelet analytical tool for isolating and evaluating cavitation-induced hemolysis generated during mechanical heart valve closure

Luke H. Herbertson, Steven Deutsch, Keefe B. Manning

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cavitation formed during the closure of mechanical heart valves (MHVs) can harm nearby blood cells and valve surfaces. In this study we focus on an approach to accurately measure cavitation energy in order to compare the effectiveness of replacement valves. Cavitation energy is difficult to measure acoustically because it is masked by other pressure fluctuations in the body or system. To improve upon currently used analytical techniques, a wavelet isolation technique was developed to quantify cavitation energy. With this method, acoustic signals captured by a hydrophone are decomposed, denoised, and then reconstructed. Wavelet analysis should prove to be particularly valuable in vivo, where visual evidence of cavitation cannot be obtained.

Original languageEnglish (US)
Title of host publicationProceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007
Pages139-140
Number of pages2
StatePublished - Dec 1 2007
Event2007 ASME Summer Bioengineering Conference, SBC 2007 - Keystone, CO, United States
Duration: Jun 20 2007Jun 24 2007

Publication series

NameProceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007

Other

Other2007 ASME Summer Bioengineering Conference, SBC 2007
CountryUnited States
CityKeystone, CO
Period6/20/076/24/07

Fingerprint

Cavitation
Hydrophones
Wavelet analysis
Blood
Acoustics
Cells

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Mechanical Engineering

Cite this

Herbertson, L. H., Deutsch, S., & Manning, K. B. (2007). Development of a wavelet analytical tool for isolating and evaluating cavitation-induced hemolysis generated during mechanical heart valve closure. In Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007 (pp. 139-140). (Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007).
Herbertson, Luke H. ; Deutsch, Steven ; Manning, Keefe B. / Development of a wavelet analytical tool for isolating and evaluating cavitation-induced hemolysis generated during mechanical heart valve closure. Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007. 2007. pp. 139-140 (Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007).
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Herbertson, LH, Deutsch, S & Manning, KB 2007, Development of a wavelet analytical tool for isolating and evaluating cavitation-induced hemolysis generated during mechanical heart valve closure. in Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007. Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007, pp. 139-140, 2007 ASME Summer Bioengineering Conference, SBC 2007, Keystone, CO, United States, 6/20/07.

Development of a wavelet analytical tool for isolating and evaluating cavitation-induced hemolysis generated during mechanical heart valve closure. / Herbertson, Luke H.; Deutsch, Steven; Manning, Keefe B.

Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007. 2007. p. 139-140 (Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Herbertson LH, Deutsch S, Manning KB. Development of a wavelet analytical tool for isolating and evaluating cavitation-induced hemolysis generated during mechanical heart valve closure. In Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007. 2007. p. 139-140. (Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007).