TY - JOUR
T1 - Development of urine standard reference materials for metabolites of organic chemicals including polycyclic aromatic hydrocarbons, phthalates, phenols, parabens, and volatile organic compounds
AU - Schantz, Michele M.
AU - Benner, Bruce A.
AU - Heckert, N. Alan
AU - Sander, Lane C.
AU - Sharpless, Katherine E.
AU - Vander Pol, Stacy S.
AU - Vasquez, Y.
AU - Villegas, M.
AU - Wise, Stephen A.
AU - Alwis, K. Udeni
AU - Blount, Benjamin C.
AU - Calafat, Antonia M.
AU - Li, Zheng
AU - Silva, Manori J.
AU - Ye, Xiaoyun
AU - Gaudreau, Éric
AU - Patterson, Donald G.
AU - Sjödin, Andreas
N1 - Publisher Copyright:
© 2015 Springer-Verlag Berlin Heidelberg (outside the USA).
PY - 2015/4/3
Y1 - 2015/4/3
N2 - Two new Standard Reference Materials (SRMs), SRM 3672 Organic Contaminants in Smokers' Urine (Frozen) and SRM 3673 Organic Contaminants in Non-Smokers' Urine (Frozen), have been developed in support of studies for assessment of human exposure to select organic environmental contaminants. Collaborations among three organizations resulted in certified values for 11 hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) and reference values for 11 phthalate metabolites, 8 environmental phenols and parabens, and 24 volatile organic compound (VOC) metabolites. Reference values are also available for creatinine and the free forms of caffeine, theobromine, ibuprofen, nicotine, cotinine, and 3-hydroxycotinine. These are the first urine Certified Reference Materials characterized for metabolites of organic environmental contaminants. Noteworthy, the mass fractions of the environmental organic contaminants in the two SRMs are within the ranges reported in population survey studies such as the National Health and Nutrition Examination Survey (NHANES) and the Canadian Health Measures Survey (CHMS). These SRMs will be useful as quality control samples for ensuring compatibility of results among population survey studies and will fill a void to assess the accuracy of analytical methods used in studies monitoring human exposure to these organic environmental contaminants. [Figure not available: see fulltext.]
AB - Two new Standard Reference Materials (SRMs), SRM 3672 Organic Contaminants in Smokers' Urine (Frozen) and SRM 3673 Organic Contaminants in Non-Smokers' Urine (Frozen), have been developed in support of studies for assessment of human exposure to select organic environmental contaminants. Collaborations among three organizations resulted in certified values for 11 hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) and reference values for 11 phthalate metabolites, 8 environmental phenols and parabens, and 24 volatile organic compound (VOC) metabolites. Reference values are also available for creatinine and the free forms of caffeine, theobromine, ibuprofen, nicotine, cotinine, and 3-hydroxycotinine. These are the first urine Certified Reference Materials characterized for metabolites of organic environmental contaminants. Noteworthy, the mass fractions of the environmental organic contaminants in the two SRMs are within the ranges reported in population survey studies such as the National Health and Nutrition Examination Survey (NHANES) and the Canadian Health Measures Survey (CHMS). These SRMs will be useful as quality control samples for ensuring compatibility of results among population survey studies and will fill a void to assess the accuracy of analytical methods used in studies monitoring human exposure to these organic environmental contaminants. [Figure not available: see fulltext.]
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U2 - 10.1007/s00216-014-8441-0
DO - 10.1007/s00216-014-8441-0
M3 - Article
C2 - 25651899
AN - SCOPUS:84940437360
VL - 407
SP - 2945
EP - 2954
JO - Fresenius Zeitschrift fur Analytische Chemie
JF - Fresenius Zeitschrift fur Analytische Chemie
SN - 0016-1152
IS - 11
ER -