Diagnostic criteria for proliferative hepatic lesions in brown bullhead Ameiurus nebulosus

Vicki S. Blazer, John W. Fournie, Jeffrey C. Wolf, Marilyn J. Wolfe

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Brown bullhead Ameiurus nebulosus is used as indicator species for contaminant effects at areas of concern (AOC) in the Great Lakes and other areas. One of the beneficial use impairments at numerous AOC is 'fish tumors and other deformities'. An impairment occurs when the prevalence of fish tumors and other deformities exceeds those at unimpacted or control sites or when survey data confirm the presence of neoplastic or preneoplastic liver lesions in bullhead or white sucker Catostomus commersonii. Numerous surveys have been conducted over the years assessing neoplasia in these fishes, both liver and skin tumors. However, a major problem in comparing the results has been a lack of consistent criteria for evaluating histological changes in bullhead livers. As individual AOC develop and implement remedial action plans, realistic and attainable delisting targets need to be specified. For this to occur and be consistent from site to site there must be standardization of the criteria being used to evaluate specific impairments. In this report, specific diagnostic criteria are provided for both non-neoplastic and neoplastic proliferative hepatocellular and biliary lesions. These criteria should assist fish pathologists in describing and categorizing proliferative liver lesions from brown bullhead.

Original languageEnglish (US)
Pages (from-to)19-30
Number of pages12
JournalDiseases of Aquatic Organisms
Volume72
Issue number1
DOIs
StatePublished - Sep 14 2006

Fingerprint

Ameiurus
lesion
lesions (animal)
tumor
liver
fish
neoplasms
liver neoplasms
action plan
Great Lakes
standardization
indicator species
skin
pollutant
lake
Catostomus commersonii

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Aquatic Science

Cite this

Blazer, Vicki S. ; Fournie, John W. ; Wolf, Jeffrey C. ; Wolfe, Marilyn J. / Diagnostic criteria for proliferative hepatic lesions in brown bullhead Ameiurus nebulosus. In: Diseases of Aquatic Organisms. 2006 ; Vol. 72, No. 1. pp. 19-30.
@article{1a41a5d3149f416fa78b1a7a247d1315,
title = "Diagnostic criteria for proliferative hepatic lesions in brown bullhead Ameiurus nebulosus",
abstract = "Brown bullhead Ameiurus nebulosus is used as indicator species for contaminant effects at areas of concern (AOC) in the Great Lakes and other areas. One of the beneficial use impairments at numerous AOC is 'fish tumors and other deformities'. An impairment occurs when the prevalence of fish tumors and other deformities exceeds those at unimpacted or control sites or when survey data confirm the presence of neoplastic or preneoplastic liver lesions in bullhead or white sucker Catostomus commersonii. Numerous surveys have been conducted over the years assessing neoplasia in these fishes, both liver and skin tumors. However, a major problem in comparing the results has been a lack of consistent criteria for evaluating histological changes in bullhead livers. As individual AOC develop and implement remedial action plans, realistic and attainable delisting targets need to be specified. For this to occur and be consistent from site to site there must be standardization of the criteria being used to evaluate specific impairments. In this report, specific diagnostic criteria are provided for both non-neoplastic and neoplastic proliferative hepatocellular and biliary lesions. These criteria should assist fish pathologists in describing and categorizing proliferative liver lesions from brown bullhead.",
author = "Blazer, {Vicki S.} and Fournie, {John W.} and Wolf, {Jeffrey C.} and Wolfe, {Marilyn J.}",
year = "2006",
month = "9",
day = "14",
doi = "10.3354/dao072019",
language = "English (US)",
volume = "72",
pages = "19--30",
journal = "Diseases of Aquatic Organisms",
issn = "0177-5103",
publisher = "Inter-Research",
number = "1",

}

Diagnostic criteria for proliferative hepatic lesions in brown bullhead Ameiurus nebulosus. / Blazer, Vicki S.; Fournie, John W.; Wolf, Jeffrey C.; Wolfe, Marilyn J.

In: Diseases of Aquatic Organisms, Vol. 72, No. 1, 14.09.2006, p. 19-30.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Diagnostic criteria for proliferative hepatic lesions in brown bullhead Ameiurus nebulosus

AU - Blazer, Vicki S.

AU - Fournie, John W.

AU - Wolf, Jeffrey C.

AU - Wolfe, Marilyn J.

PY - 2006/9/14

Y1 - 2006/9/14

N2 - Brown bullhead Ameiurus nebulosus is used as indicator species for contaminant effects at areas of concern (AOC) in the Great Lakes and other areas. One of the beneficial use impairments at numerous AOC is 'fish tumors and other deformities'. An impairment occurs when the prevalence of fish tumors and other deformities exceeds those at unimpacted or control sites or when survey data confirm the presence of neoplastic or preneoplastic liver lesions in bullhead or white sucker Catostomus commersonii. Numerous surveys have been conducted over the years assessing neoplasia in these fishes, both liver and skin tumors. However, a major problem in comparing the results has been a lack of consistent criteria for evaluating histological changes in bullhead livers. As individual AOC develop and implement remedial action plans, realistic and attainable delisting targets need to be specified. For this to occur and be consistent from site to site there must be standardization of the criteria being used to evaluate specific impairments. In this report, specific diagnostic criteria are provided for both non-neoplastic and neoplastic proliferative hepatocellular and biliary lesions. These criteria should assist fish pathologists in describing and categorizing proliferative liver lesions from brown bullhead.

AB - Brown bullhead Ameiurus nebulosus is used as indicator species for contaminant effects at areas of concern (AOC) in the Great Lakes and other areas. One of the beneficial use impairments at numerous AOC is 'fish tumors and other deformities'. An impairment occurs when the prevalence of fish tumors and other deformities exceeds those at unimpacted or control sites or when survey data confirm the presence of neoplastic or preneoplastic liver lesions in bullhead or white sucker Catostomus commersonii. Numerous surveys have been conducted over the years assessing neoplasia in these fishes, both liver and skin tumors. However, a major problem in comparing the results has been a lack of consistent criteria for evaluating histological changes in bullhead livers. As individual AOC develop and implement remedial action plans, realistic and attainable delisting targets need to be specified. For this to occur and be consistent from site to site there must be standardization of the criteria being used to evaluate specific impairments. In this report, specific diagnostic criteria are provided for both non-neoplastic and neoplastic proliferative hepatocellular and biliary lesions. These criteria should assist fish pathologists in describing and categorizing proliferative liver lesions from brown bullhead.

UR - http://www.scopus.com/inward/record.url?scp=33750164071&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33750164071&partnerID=8YFLogxK

U2 - 10.3354/dao072019

DO - 10.3354/dao072019

M3 - Article

C2 - 17067070

AN - SCOPUS:33750164071

VL - 72

SP - 19

EP - 30

JO - Diseases of Aquatic Organisms

JF - Diseases of Aquatic Organisms

SN - 0177-5103

IS - 1

ER -