Dietary control of cancer

Karam El-Bayoumy, F. L. Chung, John Richie, B. S. Reddy, L. Cohen, J. Weisburger, E. L. Wynder

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Many laboratory studies and human epidemiological data suggest that most cancer deaths are attributable to lifestyle, including nutritional factors and tobacco and alcohol consumption. Tobacco consumption is causally related to cancer of the lung, mouth, larynx, esophagus, bladder, kidney, and pancreas. Nutrients and non-nutrient dietary components probably account for cancer of the colon, breast, prostate, and stomach. This report is based on literature and our own data pertaining to the role of dietary fat, calories, and fiber in the development of colon and breast cancer. We also discuss the evidence from epidemiological, mechanistic, and preclinical efficacy studies indicating a protective effect of micronutrients, non- nutrients, and certain antioxidants in food against oral and lung cancers. Given the continuing cancer burden and the relatively slow impact of proven cancer treatment strategies in reducing cancer mortality, it is essential to evaluate promising nutrients and non-nutrients in foods as chemopreventive agents in persons at increased risk for cancer. Development of reliable intermediate biomarkers is valuable for clinical chemoprevention intervention trials. The purpose of this report is to provide the reader with plausible approaches to cancer control.

Original languageEnglish (US)
Pages (from-to)211-223
Number of pages13
JournalProceedings of the Society for Experimental Biology and Medicine
Volume216
Issue number2
StatePublished - Nov 1 1997

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Nutrients
Tobacco
Food
Neoplasms
Oncology
Micronutrients
Mouth Neoplasms
Dietary Fats
Tobacco Use
Biomarkers
Colonic Neoplasms
Lung Neoplasms
Antioxidants
Alcohols
Breast Neoplasms
Fibers
Chemoprevention
Dietary Fiber
Larynx
Alcohol Drinking

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

El-Bayoumy, K., Chung, F. L., Richie, J., Reddy, B. S., Cohen, L., Weisburger, J., & Wynder, E. L. (1997). Dietary control of cancer. Proceedings of the Society for Experimental Biology and Medicine, 216(2), 211-223.
El-Bayoumy, Karam ; Chung, F. L. ; Richie, John ; Reddy, B. S. ; Cohen, L. ; Weisburger, J. ; Wynder, E. L. / Dietary control of cancer. In: Proceedings of the Society for Experimental Biology and Medicine. 1997 ; Vol. 216, No. 2. pp. 211-223.
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El-Bayoumy, K, Chung, FL, Richie, J, Reddy, BS, Cohen, L, Weisburger, J & Wynder, EL 1997, 'Dietary control of cancer', Proceedings of the Society for Experimental Biology and Medicine, vol. 216, no. 2, pp. 211-223.

Dietary control of cancer. / El-Bayoumy, Karam; Chung, F. L.; Richie, John; Reddy, B. S.; Cohen, L.; Weisburger, J.; Wynder, E. L.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 216, No. 2, 01.11.1997, p. 211-223.

Research output: Contribution to journalArticle

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El-Bayoumy K, Chung FL, Richie J, Reddy BS, Cohen L, Weisburger J et al. Dietary control of cancer. Proceedings of the Society for Experimental Biology and Medicine. 1997 Nov 1;216(2):211-223.