Difference of helicobacter pylori colonization in recurrent inflammatory and simple hyperplastic tonsil tissues

Hsin Ching Lin, Pei Yin Wu, Michael Friedman, Hsueh Wen Chang, Meghan Wilson

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Objective: To investigate the difference in colonization by Helicobacter pylori between recurrent inflammatory and normal hyperplastic human palatine tonsil tissues. Design: A retrospective review of a prospective data set. Setting: Tertiary referral center. Patients: Patients undergoing tonsillectomy for a variety of reasons had routine screening for H pylori. Medical records of all patients who underwent tonsillectomy were reviewed to identify (1) indications for surgery and (2) presence or absence of H pylori in the specimen. All medical records that had information on H pylori were included. Patients were divided into the following 2 groups: those having tonsillectomy for chronic recurrent tonsillitis and those having tonsillectomy for sleeprelated breathing disorders (SRBDs) with no recent history of tonsillitis. Results: There were 44 patients in the tonsillitis group (18 women and 26 men; mean age, 28.6 years) and 50 patients in the SRBD group (11 women and 39 men; mean age, 33.6 years). Of 94 patients the Pronto Dry test results were positive in 33 (35%) and negative in 61 (65%). The H pylori positive rates in the tonsillitis and SRBD groups were 48% (21 of 44) and 24% (12 of 50), respectively (P<.001). Conclusions: Helicobacter pylori can colonize in human palatine tonsil tissues. A significantly higher positiveHpylori rate was present in the tonsillitis group (48%) compared with the SRBD group (24%). Based on this finding, future studies should be performed to elucidate whether eradication therapy for H pylori is effective in decreasing recurrent inflammation of human palatine tonsils.

Original languageEnglish (US)
Pages (from-to)468-470
Number of pages3
JournalArchives of Otolaryngology - Head and Neck Surgery
Volume136
Issue number5
DOIs
StatePublished - May 2010

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

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