Differential susceptibility to comorbid drug abuse and violence

Research output: Contribution to journalReview article

32 Citations (Scopus)

Abstract

Although many psychoactive substances have been associated with violent behavior, only a subgroup manifests excessively aggressive behavior when sober or intoxicated. Theories to explain addictive behaviors in general may directly relate to the specific proclivity to exhibit excessive aggression in this subset of users. Certain personality traits and cognitive deficits coexist in individuals prone to both drug abuse and violence, suggesting a common origin. Because these excessive and compulsive behaviors have been linked with aberrations in the metabolism and activity of the neurotransmitters dopamine and serotonin, their origins may be partly genetic or biological. Alterations in neurotransmitter function influence activities within the brain's reward center to perturb nervous system arousal levels, thereby increasing stimulation-seeking behaviors. Manifestations of these neurobiological aberrations can be measured in physiological and biochemical processes that serve to mediate these behavioral and psychological outcomes.

Original languageEnglish (US)
Pages (from-to)859-890
Number of pages32
JournalJournal of Drug Issues
Volume28
Issue number4
DOIs
StatePublished - Jan 1 1998

Fingerprint

drug abuse
Violence
Substance-Related Disorders
violence
Neurotransmitter Agents
Biochemical Phenomena
Compulsive Behavior
Physiological Phenomena
Addictive Behavior
Arousal
Aggression
Reward
Nervous System
Personality
Dopamine
Serotonin
aggressive behavior
personality traits
Psychology
aggression

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Health(social science)
  • Public Health, Environmental and Occupational Health
  • Psychiatry and Mental health

Cite this

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Differential susceptibility to comorbid drug abuse and violence. / Fishbein, Diana H.

In: Journal of Drug Issues, Vol. 28, No. 4, 01.01.1998, p. 859-890.

Research output: Contribution to journalReview article

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