TY - JOUR
T1 - Diffuse coronary artery disease in diabetic patients. Fact or fiction?
AU - Dortimer, A. C.
AU - Shenoy, P. N.
AU - Shiroff, R. A.
AU - Leaman, D. M.
AU - Babb, J. D.
AU - Liedtke, A. J.
AU - Zelis, R.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1978
Y1 - 1978
N2 - To compare angiographically-determined coronary artery disease in diabetic patients with controls, 1,653 patients coming to cardiac catheterization were reviewed retrospectively to find 37 diabetic and 79 control patients matched for sex, age (±3 years), and risk factors (hypertension, hyperlipidemia, and smoking). The severity of coronary artery disease was assessed using an angiographic grading system. The following results were obtained: 16 of 37 diabetic patients (43%) had three-vessel disease compared to 20 of 79 controls (25%). Seventy-six of 111 (68%) diabetic vessels were disease compared to 110 of 237 control vessels (46%) (P<0.005). The total coronary score reflecting total extent of disease for diabetic patients was 371 (mean 10.0±1.0 (SEM)) compared to 594 for controls (mean 7.5±0.7, P<0.01). Diabetic patients had a statistically similar number of diffusely diseased vessels as controls (28% vs 22%). There were only three of 76 diabetic vessels (4%) considered inoperable compared to seven of 110 (6%) control vessels. The authors conclude that diabetic patients with chest pain have more coronary artery disease than nondiabetics, but no more diffuse or inoperable disease.
AB - To compare angiographically-determined coronary artery disease in diabetic patients with controls, 1,653 patients coming to cardiac catheterization were reviewed retrospectively to find 37 diabetic and 79 control patients matched for sex, age (±3 years), and risk factors (hypertension, hyperlipidemia, and smoking). The severity of coronary artery disease was assessed using an angiographic grading system. The following results were obtained: 16 of 37 diabetic patients (43%) had three-vessel disease compared to 20 of 79 controls (25%). Seventy-six of 111 (68%) diabetic vessels were disease compared to 110 of 237 control vessels (46%) (P<0.005). The total coronary score reflecting total extent of disease for diabetic patients was 371 (mean 10.0±1.0 (SEM)) compared to 594 for controls (mean 7.5±0.7, P<0.01). Diabetic patients had a statistically similar number of diffusely diseased vessels as controls (28% vs 22%). There were only three of 76 diabetic vessels (4%) considered inoperable compared to seven of 110 (6%) control vessels. The authors conclude that diabetic patients with chest pain have more coronary artery disease than nondiabetics, but no more diffuse or inoperable disease.
UR - http://www.scopus.com/inward/record.url?scp=0017797991&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017797991&partnerID=8YFLogxK
U2 - 10.1161/01.CIR.57.1.133
DO - 10.1161/01.CIR.57.1.133
M3 - Article
C2 - 618380
AN - SCOPUS:0017797991
VL - 57
SP - 133
EP - 136
JO - [No source information available]
JF - [No source information available]
SN - 0042-1215
IS - 1
ER -