Diffuse coronary artery disease in diabetic patients. Fact or fiction?

A. C. Dortimer, P. N. Shenoy, R. A. Shiroff, D. M. Leaman, J. D. Babb, A. J. Liedtke, R. Zelis

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Abstract

To compare angiographically-determined coronary artery disease in diabetic patients with controls, 1,653 patients coming to cardiac catheterization were reviewed retrospectively to find 37 diabetic and 79 control patients matched for sex, age (±3 years), and risk factors (hypertension, hyperlipidemia, and smoking). The severity of coronary artery disease was assessed using an angiographic grading system. The following results were obtained: 16 of 37 diabetic patients (43%) had three-vessel disease compared to 20 of 79 controls (25%). Seventy-six of 111 (68%) diabetic vessels were disease compared to 110 of 237 control vessels (46%) (P<0.005). The total coronary score reflecting total extent of disease for diabetic patients was 371 (mean 10.0±1.0 (SEM)) compared to 594 for controls (mean 7.5±0.7, P<0.01). Diabetic patients had a statistically similar number of diffusely diseased vessels as controls (28% vs 22%). There were only three of 76 diabetic vessels (4%) considered inoperable compared to seven of 110 (6%) control vessels. The authors conclude that diabetic patients with chest pain have more coronary artery disease than nondiabetics, but no more diffuse or inoperable disease.

Original languageEnglish (US)
Pages (from-to)133-136
Number of pages4
JournalUnknown Journal
Volume57
Issue number1
DOIs
StatePublished - Jan 1 1978

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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    Dortimer, A. C., Shenoy, P. N., Shiroff, R. A., Leaman, D. M., Babb, J. D., Liedtke, A. J., & Zelis, R. (1978). Diffuse coronary artery disease in diabetic patients. Fact or fiction? Unknown Journal, 57(1), 133-136. https://doi.org/10.1161/01.CIR.57.1.133