Diffusion tensor brain MR imaging in X-linked cerebral adrenoleukodystrophy

R. Ito, Elias R. Melhem, S. Mori, F. S. Eichler, G. V. Raymond, H. W. Moser

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Abstract

Brain diffusion tensor MRI of 11 boys with X-linked adrenoleukodystrophy was performed. The authors determined quantitative isotropic apparent diffusion coefficient (ADCi) and fractional anisotropy (FA) values in the white matter. ADCi and FA values in the affected white matter were significantly different from those in normal-appearing white matter. Zonal ADCi and FA gradations, which might originate from well-established histopathologic zonal changes, existed within affected white matter.

Original languageEnglish (US)
Pages (from-to)544-547
Number of pages4
JournalNeurology
Volume56
Issue number4
DOIs
Publication statusPublished - Feb 27 2001

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All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Ito, R., Melhem, E. R., Mori, S., Eichler, F. S., Raymond, G. V., & Moser, H. W. (2001). Diffusion tensor brain MR imaging in X-linked cerebral adrenoleukodystrophy. Neurology, 56(4), 544-547. https://doi.org/10.1212/WNL.56.4.544