Direct comparison of Neuroform and Enterprise stents in the treatment of wide-necked intracranial aneurysms

C. R. Durst, P. Khan, J. Gaughen, J. Patrie, R. M. Starke, P. Conant, Kenneth Liu, M. E. Jensen, A. J. Evans

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Aim To compare the complications and outcomes of Neuroform and Enterprise stents in the treatment of unruptured wide-necked aneurysms. Materials and methods Under the auspices of the institutional review board, a review of a prospectively collected patient log identified 130 patients who underwent elective stent-assisted coil embolization of a wide-necked aneurysm, including 53 patients treated with an Enterprise stent and 77 patients treated with a Neuroform stent. Immediate and long-term clinical and radiographic outcomes were recorded for all patients. All patient data were handled in accordance with Health Insurance Portability and Accountability Act of 1996 (HIPAA) regulations. Results The technical success rate was 94%. Overall morbidity was 15% with Enterprise stents and 3% with Neuroform stents (p = 0.020). However, the type of stent used was not predictive of clinical outcomes as measured by the modified Rankin scale. In a multivariate analysis, the use of a Neuroform stent was one of the predictors of retreatment (p = 0.034). Conclusion Multivariate analyses identified the use of Neuroform stents as an independent predictor of the need for retreatment and the use of Enterprise stents as an independent predictor of morbidity. However, the type of stent was not predictive of clinical outcome as measured by the modified Rankin scale.

Original languageEnglish (US)
Pages (from-to)e471-e476
JournalClinical Radiology
Volume69
Issue number12
DOIs
StatePublished - Dec 1 2014

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Intracranial Aneurysm
Stents
Therapeutics
Retreatment
Aneurysm
Multivariate Analysis
Health Insurance Portability and Accountability Act
Morbidity
Research Ethics Committees

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Durst, C. R., Khan, P., Gaughen, J., Patrie, J., Starke, R. M., Conant, P., ... Evans, A. J. (2014). Direct comparison of Neuroform and Enterprise stents in the treatment of wide-necked intracranial aneurysms. Clinical Radiology, 69(12), e471-e476. https://doi.org/10.1016/j.crad.2014.07.015
Durst, C. R. ; Khan, P. ; Gaughen, J. ; Patrie, J. ; Starke, R. M. ; Conant, P. ; Liu, Kenneth ; Jensen, M. E. ; Evans, A. J. / Direct comparison of Neuroform and Enterprise stents in the treatment of wide-necked intracranial aneurysms. In: Clinical Radiology. 2014 ; Vol. 69, No. 12. pp. e471-e476.
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Durst, CR, Khan, P, Gaughen, J, Patrie, J, Starke, RM, Conant, P, Liu, K, Jensen, ME & Evans, AJ 2014, 'Direct comparison of Neuroform and Enterprise stents in the treatment of wide-necked intracranial aneurysms', Clinical Radiology, vol. 69, no. 12, pp. e471-e476. https://doi.org/10.1016/j.crad.2014.07.015

Direct comparison of Neuroform and Enterprise stents in the treatment of wide-necked intracranial aneurysms. / Durst, C. R.; Khan, P.; Gaughen, J.; Patrie, J.; Starke, R. M.; Conant, P.; Liu, Kenneth; Jensen, M. E.; Evans, A. J.

In: Clinical Radiology, Vol. 69, No. 12, 01.12.2014, p. e471-e476.

Research output: Contribution to journalArticle

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T1 - Direct comparison of Neuroform and Enterprise stents in the treatment of wide-necked intracranial aneurysms

AU - Durst, C. R.

AU - Khan, P.

AU - Gaughen, J.

AU - Patrie, J.

AU - Starke, R. M.

AU - Conant, P.

AU - Liu, Kenneth

AU - Jensen, M. E.

AU - Evans, A. J.

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Aim To compare the complications and outcomes of Neuroform and Enterprise stents in the treatment of unruptured wide-necked aneurysms. Materials and methods Under the auspices of the institutional review board, a review of a prospectively collected patient log identified 130 patients who underwent elective stent-assisted coil embolization of a wide-necked aneurysm, including 53 patients treated with an Enterprise stent and 77 patients treated with a Neuroform stent. Immediate and long-term clinical and radiographic outcomes were recorded for all patients. All patient data were handled in accordance with Health Insurance Portability and Accountability Act of 1996 (HIPAA) regulations. Results The technical success rate was 94%. Overall morbidity was 15% with Enterprise stents and 3% with Neuroform stents (p = 0.020). However, the type of stent used was not predictive of clinical outcomes as measured by the modified Rankin scale. In a multivariate analysis, the use of a Neuroform stent was one of the predictors of retreatment (p = 0.034). Conclusion Multivariate analyses identified the use of Neuroform stents as an independent predictor of the need for retreatment and the use of Enterprise stents as an independent predictor of morbidity. However, the type of stent was not predictive of clinical outcome as measured by the modified Rankin scale.

AB - Aim To compare the complications and outcomes of Neuroform and Enterprise stents in the treatment of unruptured wide-necked aneurysms. Materials and methods Under the auspices of the institutional review board, a review of a prospectively collected patient log identified 130 patients who underwent elective stent-assisted coil embolization of a wide-necked aneurysm, including 53 patients treated with an Enterprise stent and 77 patients treated with a Neuroform stent. Immediate and long-term clinical and radiographic outcomes were recorded for all patients. All patient data were handled in accordance with Health Insurance Portability and Accountability Act of 1996 (HIPAA) regulations. Results The technical success rate was 94%. Overall morbidity was 15% with Enterprise stents and 3% with Neuroform stents (p = 0.020). However, the type of stent used was not predictive of clinical outcomes as measured by the modified Rankin scale. In a multivariate analysis, the use of a Neuroform stent was one of the predictors of retreatment (p = 0.034). Conclusion Multivariate analyses identified the use of Neuroform stents as an independent predictor of the need for retreatment and the use of Enterprise stents as an independent predictor of morbidity. However, the type of stent was not predictive of clinical outcome as measured by the modified Rankin scale.

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