Transition-metal hydrides generate α-alkoxy radicals by H• transfer to enol ethers. We have measured the rate constant for transfer from CpCr-(CO)3H to n-butyl vinyl ether and have examined the chemistry of radicals generated by such transfers. Radicals from appropriate substrates undergo 5-exo cyclization, with higher diastereoselectivity than the analogous allcarbon radicals. From such radicals it is straightforward to make substituted tetrahydrofurans.
All Science Journal Classification (ASJC) codes
- Colloid and Surface Chemistry