Directed self-assembly of inorganic redox complexes with artificial peptide scaffolds

Research output: Contribution to journalReview article

20 Citations (Scopus)

Abstract

An ongoing challenge in the construction of supramolecular systems is controlling the relative geometry of functional redox species for molecular electronics devices, including wires, switches, and gates. This review focuses on the use of artificial peptide strands to assemble inorganic complexes that are redox active. These approaches toward macromolecular assembly use varying oligoamide backbones and assembly motifs that grew from earlier reports of single oligolysine or proline chains containing pendant redox species that undergo photoinduced charge separation. Recently, peptide nucleic acid chains that form double-stranded duplexes analogous to DNA by hydrogen bonding of complementary base pairs have been modified to contain metal complexes. In these structures, hydrogen bonding and metal coordination combine to form crosslinks between the PNA strands. Finally, a family of structures is described that is based on an aminoethylglycine scaffold with pendant metal coordination sites, but without intervening nucleic acid base pairs. These structures form multimetallic complexes that are either single- or double-stranded, or that form hairpin loop structures. These motifs for using artificial peptide strands for self-assembly hold electron donors and acceptors in relative positions that provide structural connectivity and permit electron transfers between linked metal complexes. This is a new approach for creating polyfunctional redox architectures that could ultimately enable the construction of potentially large and complex molecular electronics devices.

Original languageEnglish (US)
Pages (from-to)2416-2428
Number of pages13
JournalCoordination Chemistry Reviews
Volume254
Issue number19-20
DOIs
StatePublished - Oct 1 2010

Fingerprint

Scaffolds (biology)
Scaffolds
Self assembly
Peptides
peptides
self assembly
strands
Molecular electronics
molecular electronics
Coordination Complexes
nucleic acids
Metal complexes
metals
Hydrogen bonds
assembly
Metals
Peptide Nucleic Acids
Electrons
Nucleic acids
hydrogen

All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

Cite this

@article{daa05700abe44450bcc049e07cd92bdb,
title = "Directed self-assembly of inorganic redox complexes with artificial peptide scaffolds",
abstract = "An ongoing challenge in the construction of supramolecular systems is controlling the relative geometry of functional redox species for molecular electronics devices, including wires, switches, and gates. This review focuses on the use of artificial peptide strands to assemble inorganic complexes that are redox active. These approaches toward macromolecular assembly use varying oligoamide backbones and assembly motifs that grew from earlier reports of single oligolysine or proline chains containing pendant redox species that undergo photoinduced charge separation. Recently, peptide nucleic acid chains that form double-stranded duplexes analogous to DNA by hydrogen bonding of complementary base pairs have been modified to contain metal complexes. In these structures, hydrogen bonding and metal coordination combine to form crosslinks between the PNA strands. Finally, a family of structures is described that is based on an aminoethylglycine scaffold with pendant metal coordination sites, but without intervening nucleic acid base pairs. These structures form multimetallic complexes that are either single- or double-stranded, or that form hairpin loop structures. These motifs for using artificial peptide strands for self-assembly hold electron donors and acceptors in relative positions that provide structural connectivity and permit electron transfers between linked metal complexes. This is a new approach for creating polyfunctional redox architectures that could ultimately enable the construction of potentially large and complex molecular electronics devices.",
author = "Myers, {Carl P.} and Williams, {Mary Elizabeth}",
year = "2010",
month = "10",
day = "1",
doi = "10.1016/j.ccr.2010.02.018",
language = "English (US)",
volume = "254",
pages = "2416--2428",
journal = "Coordination Chemistry Reviews",
issn = "0010-8545",
publisher = "Elsevier",
number = "19-20",

}

Directed self-assembly of inorganic redox complexes with artificial peptide scaffolds. / Myers, Carl P.; Williams, Mary Elizabeth.

In: Coordination Chemistry Reviews, Vol. 254, No. 19-20, 01.10.2010, p. 2416-2428.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Directed self-assembly of inorganic redox complexes with artificial peptide scaffolds

AU - Myers, Carl P.

AU - Williams, Mary Elizabeth

PY - 2010/10/1

Y1 - 2010/10/1

N2 - An ongoing challenge in the construction of supramolecular systems is controlling the relative geometry of functional redox species for molecular electronics devices, including wires, switches, and gates. This review focuses on the use of artificial peptide strands to assemble inorganic complexes that are redox active. These approaches toward macromolecular assembly use varying oligoamide backbones and assembly motifs that grew from earlier reports of single oligolysine or proline chains containing pendant redox species that undergo photoinduced charge separation. Recently, peptide nucleic acid chains that form double-stranded duplexes analogous to DNA by hydrogen bonding of complementary base pairs have been modified to contain metal complexes. In these structures, hydrogen bonding and metal coordination combine to form crosslinks between the PNA strands. Finally, a family of structures is described that is based on an aminoethylglycine scaffold with pendant metal coordination sites, but without intervening nucleic acid base pairs. These structures form multimetallic complexes that are either single- or double-stranded, or that form hairpin loop structures. These motifs for using artificial peptide strands for self-assembly hold electron donors and acceptors in relative positions that provide structural connectivity and permit electron transfers between linked metal complexes. This is a new approach for creating polyfunctional redox architectures that could ultimately enable the construction of potentially large and complex molecular electronics devices.

AB - An ongoing challenge in the construction of supramolecular systems is controlling the relative geometry of functional redox species for molecular electronics devices, including wires, switches, and gates. This review focuses on the use of artificial peptide strands to assemble inorganic complexes that are redox active. These approaches toward macromolecular assembly use varying oligoamide backbones and assembly motifs that grew from earlier reports of single oligolysine or proline chains containing pendant redox species that undergo photoinduced charge separation. Recently, peptide nucleic acid chains that form double-stranded duplexes analogous to DNA by hydrogen bonding of complementary base pairs have been modified to contain metal complexes. In these structures, hydrogen bonding and metal coordination combine to form crosslinks between the PNA strands. Finally, a family of structures is described that is based on an aminoethylglycine scaffold with pendant metal coordination sites, but without intervening nucleic acid base pairs. These structures form multimetallic complexes that are either single- or double-stranded, or that form hairpin loop structures. These motifs for using artificial peptide strands for self-assembly hold electron donors and acceptors in relative positions that provide structural connectivity and permit electron transfers between linked metal complexes. This is a new approach for creating polyfunctional redox architectures that could ultimately enable the construction of potentially large and complex molecular electronics devices.

UR - http://www.scopus.com/inward/record.url?scp=77955418154&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955418154&partnerID=8YFLogxK

U2 - 10.1016/j.ccr.2010.02.018

DO - 10.1016/j.ccr.2010.02.018

M3 - Review article

AN - SCOPUS:77955418154

VL - 254

SP - 2416

EP - 2428

JO - Coordination Chemistry Reviews

JF - Coordination Chemistry Reviews

SN - 0010-8545

IS - 19-20

ER -