Directing placement, alignment, and transport of magnet nanoparticle labeled microtubules

Mary Elizabeth Williams, Benjamin M. Hutchins, Mark Platt, William O. Hancock

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Microtubules are labeled with superparamagnetic CoFe2O 4 nanoparticles using biotin-streptavidin coupling. Small permanent magnets are used to attract and deposit the microtubules on kinesin-modified surfaces in aligned arrays. Nanoparticle labeling affects motility of the motor proteins due to steric hindrance, This construct is optimized using heterofunctionalized microtubules, which have near-native gliding velocities but can be directed using weak applied magnetic fields. copyright the Electrochemical Society.

Original languageEnglish (US)
Title of host publicationECS Transactions - Biological Nanostructures, Materials, and Applications
Pages1-7
Number of pages7
Edition19
DOIs
StatePublished - Dec 1 2007
EventBiological Nanostructures, Materials, and Applications - 210th ECS Meeting - Cancun, Mexico
Duration: Oct 29 2006Nov 3 2006

Publication series

NameECS Transactions
Number19
Volume3
ISSN (Print)1938-5862
ISSN (Electronic)1938-6737

Other

OtherBiological Nanostructures, Materials, and Applications - 210th ECS Meeting
CountryMexico
CityCancun
Period10/29/0611/3/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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    Williams, M. E., Hutchins, B. M., Platt, M., & Hancock, W. O. (2007). Directing placement, alignment, and transport of magnet nanoparticle labeled microtubules. In ECS Transactions - Biological Nanostructures, Materials, and Applications (19 ed., pp. 1-7). (ECS Transactions; Vol. 3, No. 19). https://doi.org/10.1149/1.2721503