Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity

Z. Tang, S. Jiang, R. Du, E. T. Petri, A. El-Telbany, P. S.O. Chan, T. Kijima, S. Dietrich, K. Matsui, M. Kobayashi, S. Sasada, N. Okamoto, H. Suzuki, K. Kawahara, T. Iwasaki, K. Nakagawa, I. Kawase, J. G. Christensen, T. Hirashima, B. HalmosR. Salgia, T. J. Boggon, J. A. Kern, P. C. Ma

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Medicine & Life Sciences