TY - JOUR
T1 - Disruptive effects of prefeeding and haloperidol administration on multiple measures of food-maintained behavior in rats
AU - Hayashi, Yusuke
AU - Wirth, Oliver
PY - 2012/3/1
Y1 - 2012/3/1
N2 - Four rats responded under a choice reaction-time procedure. At the beginning of each trial, the rats were required to hold down a center lever for a variable duration, release it following a high- or low-pitched tone, and press either a left or right lever, conditionally on the tone. Correct choices were reinforced with a probability of 95 or 05 under blinking or static houselights, respectively. After performance stabilized, disruptive effects of free access to food pellets prior to sessions (prefeeding) and intraperitoneal injection of haloperidol were examined on multiple behavioral measures (i.e., the number of trials completed, percent of correct responses, and reaction time). Resistance to prefeeding depended on the probability of food delivery for the number of trials completed and reaction time. Resistance to haloperidol, on the other hand, was not systematically affected by the probability of food delivery for all dependent measures.
AB - Four rats responded under a choice reaction-time procedure. At the beginning of each trial, the rats were required to hold down a center lever for a variable duration, release it following a high- or low-pitched tone, and press either a left or right lever, conditionally on the tone. Correct choices were reinforced with a probability of 95 or 05 under blinking or static houselights, respectively. After performance stabilized, disruptive effects of free access to food pellets prior to sessions (prefeeding) and intraperitoneal injection of haloperidol were examined on multiple behavioral measures (i.e., the number of trials completed, percent of correct responses, and reaction time). Resistance to prefeeding depended on the probability of food delivery for the number of trials completed and reaction time. Resistance to haloperidol, on the other hand, was not systematically affected by the probability of food delivery for all dependent measures.
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U2 - 10.1016/j.beproc.2011.12.011
DO - 10.1016/j.beproc.2011.12.011
M3 - Article
C2 - 22209910
AN - SCOPUS:84857138361
VL - 89
SP - 314
EP - 318
JO - Behavioural Processes
JF - Behavioural Processes
SN - 0376-6357
IS - 3
ER -