Dissecting the role of Kr-h1 brain gene expression in foraging behavior in honey bees (Apis mellifera)

B. Fussnecker, Christina M. Grozinger

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Expression of Krüppel homolog-1 (Kr-h1) in the honey bee brain is strongly associated with foraging behavior. We performed a series of studies to determine if Kr-h1 expression correlates with specific aspects of foraging. We found that Kr-h1 expression is unaffected by flight experience in male bees. Expression was unaffected by behavioral reversion of workers from foraging to brood care, suggesting that expression is not associated with the active performance of foraging, but rather with stable physiological changes. Kr-h1 expression is increased by cGMP treatment in workers, and the Kr-h1 promoter contains a conserved potential cGMP response element. Since cGMP treatment causes precocious foraging, our results suggest that Kr-h1 expression is associated with cGMP-mediated changes in the brain that occur early in the transition to foraging behavior.

Original languageEnglish (US)
Pages (from-to)515-522
Number of pages8
JournalInsect Molecular Biology
Volume17
Issue number5
DOIs
Publication statusPublished - Oct 1 2008

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All Science Journal Classification (ASJC) codes

  • Insect Science
  • Genetics
  • Molecular Biology

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