Diversity of CRISPR-Cas immune systems and molecular machines

Rodolphe Barrangou

doi:10.1186/s13059-015-0816-9

Diversity of CRISPR-Cas immune systems and molecular machines

Rodolphe Barrangou

Food Science

Research output: Contribution to journal › Review article › peer-review

49 Scopus citations

Abstract

Bacterial adaptive immunity hinges on CRISPR-Cas systems that provide DNA-encoded, RNA-mediated targeting of exogenous nucleic acids. A plethora of CRISPR molecular machines occur broadly in prokaryotic genomes, with a diversity of Cas nucleases that can be repurposed for various applications.

Original language	English (US)
Article number	247
Journal	Genome biology
Volume	16
Issue number	1
DOIs	https://doi.org/10.1186/s13059-015-0816-9
State	Published - Nov 9 2015

All Science Journal Classification (ASJC) codes

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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abstract = "Bacterial adaptive immunity hinges on CRISPR-Cas systems that provide DNA-encoded, RNA-mediated targeting of exogenous nucleic acids. A plethora of CRISPR molecular machines occur broadly in prokaryotic genomes, with a diversity of Cas nucleases that can be repurposed for various applications.",

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Diversity of CRISPR-Cas immune systems and molecular machines

Abstract

All Science Journal Classification (ASJC) codes

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