DNA Damage Discrimination at Stalled Replication Forks by the Rad5 Homologs HLTF and SHPRH

George Lucian Moldovan, Alan D. D'Andrea

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations

Abstract

In this issue of Molecular Cell, Lin et al. (2011) describe how HLTF and SHPRH, the human homologs of yeast Rad5, can discriminate between MMS-induced versus UV-induced DNA damage. The results have important implications for the suppression of damage-specific mutagenesis and for the maintenance of genomic stability.

Original languageEnglish (US)
Pages (from-to)141-143
Number of pages3
JournalMolecular cell
Volume42
Issue number2
DOIs
StatePublished - Apr 22 2011

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology

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