DNA Damage Discrimination at Stalled Replication Forks by the Rad5 Homologs HLTF and SHPRH

George-Lucian Moldovan, Alan D. D'Andrea

Research output: Contribution to journalShort survey

4 Citations (Scopus)

Abstract

In this issue of Molecular Cell, Lin et al. (2011) describe how HLTF and SHPRH, the human homologs of yeast Rad5, can discriminate between MMS-induced versus UV-induced DNA damage. The results have important implications for the suppression of damage-specific mutagenesis and for the maintenance of genomic stability.

Original languageEnglish (US)
Pages (from-to)141-143
Number of pages3
JournalMolecular Cell
Volume42
Issue number2
DOIs
StatePublished - Apr 22 2011

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Genomic Instability
Mutagenesis
DNA Damage
Yeasts
Maintenance

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology

Cite this

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abstract = "In this issue of Molecular Cell, Lin et al. (2011) describe how HLTF and SHPRH, the human homologs of yeast Rad5, can discriminate between MMS-induced versus UV-induced DNA damage. The results have important implications for the suppression of damage-specific mutagenesis and for the maintenance of genomic stability.",
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DNA Damage Discrimination at Stalled Replication Forks by the Rad5 Homologs HLTF and SHPRH. / Moldovan, George-Lucian; D'Andrea, Alan D.

In: Molecular Cell, Vol. 42, No. 2, 22.04.2011, p. 141-143.

Research output: Contribution to journalShort survey

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AU - D'Andrea, Alan D.

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