DNA Polymerases η and ζ Combine to Bypass O²-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens

Medicine & Life Sciences

• N'-nitrosonornicotine 100%
• thymidine 5'-triphosphate 84%
• Thymine 76%
• DNA Adducts 70%
• O2-(4-(3-pyridyl)-4-oxobut-1-yl)thymidine 64%
• DNA-Directed DNA Polymerase 63%
• Carcinogens 54%
• Tobacco 53%
• Yeasts 45%
• Nucleotides 45%
• 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 43%
• deoxyguanosine triphosphate 43%
• 2'-deoxycytidine 5'-triphosphate 42%
• Tobacco Products 26%
• Rodentia 23%
• Adenosine Triphosphate 21%
• In Vitro Techniques 12%

Chemical Compounds

• Thymine 60%
• Adduct 40%
• dTTP 20%
• Nucleotide 11%
• dGTP 10%
• dCTP 10%
• dATP 10%
• Kcat/Km 8%
• Thymidine 7%
• Time 2%