Do major depressive disorder and dysthymic disorder confer differential risk for suicide?

Tracy K. Witte, Katherine A. Timmons, Erin Leigh Miller, April R. Smith, Thomas E. Joiner

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Background: Although there has been a tremendous amount of research examining the risk conferred for suicide by depression in general, relatively little research examines the risk conferred by specific forms of depressive illness (e.g., dysthymic disorder, single episode versus recurrent major depressive disorder [MDD]). The purpose of the current study was to examine differences in suicidal ideation, clinician-rated suicide risk, suicide attempts, and family history of suicide in a sample of outpatients diagnosed with various forms of depressive illness. Methods: To accomplish this aim, we conducted a cluster analysis using the aforementioned suicide-related variables in a sample of 494 outpatients seen between January 2001 and July 2007 at the Florida State University Psychology Clinic. Patients were diagnosed using DSM-IV criteria. Results: Two distinct clusters emerged that were indicative of lower and higher risk for suicide. After controlling for the number of comorbid Axis I and Axis II diagnoses, the only depressive illness that significantly predicted cluster membership was recurrent MDD, which tripled an individual's likelihood of being assigned to the higher risk cluster. Limitations: The use of a cross-sectional design; the relatively low suicide risk in our sample; the relatively small number of individuals with double depression. Conclusions: Our results demonstrate the importance of both chronicity and severity of depression in terms of predicting increased suicide risk. Among the various forms of depressive illness examined, only recurrent MDD appeared to confer greater risk for suicide.

Original languageEnglish (US)
Pages (from-to)69-78
Number of pages10
JournalJournal of Affective Disorders
Volume115
Issue number1-2
DOIs
StatePublished - May 1 2009

Fingerprint

Dysthymic Disorder
Major Depressive Disorder
Suicide
Depression
Outpatients
Suicidal Ideation
Research
Diagnostic and Statistical Manual of Mental Disorders
Cluster Analysis
Psychology

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Witte, Tracy K. ; Timmons, Katherine A. ; Miller, Erin Leigh ; Smith, April R. ; Joiner, Thomas E. / Do major depressive disorder and dysthymic disorder confer differential risk for suicide?. In: Journal of Affective Disorders. 2009 ; Vol. 115, No. 1-2. pp. 69-78.
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Do major depressive disorder and dysthymic disorder confer differential risk for suicide? / Witte, Tracy K.; Timmons, Katherine A.; Miller, Erin Leigh; Smith, April R.; Joiner, Thomas E.

In: Journal of Affective Disorders, Vol. 115, No. 1-2, 01.05.2009, p. 69-78.

Research output: Contribution to journalArticle

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