Do milk-borne cytokines and hormones influence neonatal immune cell function?

Lorie A. Ellis, Andrea M. Mastro, Mary Frances Picciano

Research output: Contribution to journalArticle

56 Scopus citations

Abstract

Cytokines, growth factors and various hormones collectively control the proliferation, survival, differentiation and function of immune cells. A wide array of these compounds is present in maternal milk and ingested by neonates during a period of rapid maturation of gut-associated and peripheral lymphoid tissues. The functional consequences of most milk immunomodulatory constituents in neonates are unknown. However, there is evidence that milk prolactin acts as a developmental regulator of the neonatal immune system, supporting the premise that milk constituents with immunomodulatory activity may serve as neonatal immunodevelopment agents.

Original languageEnglish (US)
Pages (from-to)985S-988S
JournalJournal of Nutrition
Volume127
Issue number5 SUPPL.
DOIs
StatePublished - Jan 1 1997

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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