Do persistent RNA viruses fit the trade-off hypothesis of virulence evolution?

Luis M. Márquez, Marilyn J. Roossinck

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

The evolution of virulence has been studied from a number of theoretical perspectives, and a few experimental systems. Although there is no consensus on an overarching framework that covers all situations, the 'trade-off' hypothesis is a useful framework for examining the nature of symbiotic relationships between viruses and their hosts. Here we use this framework to look at persistent RNA viruses of unicellular eukaryotes and fungi that are themselves parasites of more complex eukaryotes. In these tripartite symbioses we look at the cost to the microbial host as well as the macrobial host. In some cases benefits conferred by the virus to the microbial host result in greater costs to the macrobial host, in other cases the microbial host suffers a greater cost but the macrobial host wins, and in some cases everyone wins. In all cases the trade-off hypothesis can be invoked.

Original languageEnglish (US)
Pages (from-to)556-560
Number of pages5
JournalCurrent Opinion in Virology
Volume2
Issue number5
DOIs
StatePublished - Jan 1 2012

Fingerprint

RNA Viruses
Virulence
Eukaryota
Costs and Cost Analysis
Viruses
Symbiosis
Parasites
Fungi

All Science Journal Classification (ASJC) codes

  • Virology

Cite this

@article{d162f98fb620437eb30b173a46def346,
title = "Do persistent RNA viruses fit the trade-off hypothesis of virulence evolution?",
abstract = "The evolution of virulence has been studied from a number of theoretical perspectives, and a few experimental systems. Although there is no consensus on an overarching framework that covers all situations, the 'trade-off' hypothesis is a useful framework for examining the nature of symbiotic relationships between viruses and their hosts. Here we use this framework to look at persistent RNA viruses of unicellular eukaryotes and fungi that are themselves parasites of more complex eukaryotes. In these tripartite symbioses we look at the cost to the microbial host as well as the macrobial host. In some cases benefits conferred by the virus to the microbial host result in greater costs to the macrobial host, in other cases the microbial host suffers a greater cost but the macrobial host wins, and in some cases everyone wins. In all cases the trade-off hypothesis can be invoked.",
author = "M{\'a}rquez, {Luis M.} and Roossinck, {Marilyn J.}",
year = "2012",
month = "1",
day = "1",
doi = "10.1016/j.coviro.2012.06.010",
language = "English (US)",
volume = "2",
pages = "556--560",
journal = "Current Opinion in Virology",
issn = "1879-6257",
publisher = "Elsevier BV",
number = "5",

}

Do persistent RNA viruses fit the trade-off hypothesis of virulence evolution? / Márquez, Luis M.; Roossinck, Marilyn J.

In: Current Opinion in Virology, Vol. 2, No. 5, 01.01.2012, p. 556-560.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Do persistent RNA viruses fit the trade-off hypothesis of virulence evolution?

AU - Márquez, Luis M.

AU - Roossinck, Marilyn J.

PY - 2012/1/1

Y1 - 2012/1/1

N2 - The evolution of virulence has been studied from a number of theoretical perspectives, and a few experimental systems. Although there is no consensus on an overarching framework that covers all situations, the 'trade-off' hypothesis is a useful framework for examining the nature of symbiotic relationships between viruses and their hosts. Here we use this framework to look at persistent RNA viruses of unicellular eukaryotes and fungi that are themselves parasites of more complex eukaryotes. In these tripartite symbioses we look at the cost to the microbial host as well as the macrobial host. In some cases benefits conferred by the virus to the microbial host result in greater costs to the macrobial host, in other cases the microbial host suffers a greater cost but the macrobial host wins, and in some cases everyone wins. In all cases the trade-off hypothesis can be invoked.

AB - The evolution of virulence has been studied from a number of theoretical perspectives, and a few experimental systems. Although there is no consensus on an overarching framework that covers all situations, the 'trade-off' hypothesis is a useful framework for examining the nature of symbiotic relationships between viruses and their hosts. Here we use this framework to look at persistent RNA viruses of unicellular eukaryotes and fungi that are themselves parasites of more complex eukaryotes. In these tripartite symbioses we look at the cost to the microbial host as well as the macrobial host. In some cases benefits conferred by the virus to the microbial host result in greater costs to the macrobial host, in other cases the microbial host suffers a greater cost but the macrobial host wins, and in some cases everyone wins. In all cases the trade-off hypothesis can be invoked.

UR - http://www.scopus.com/inward/record.url?scp=84867403285&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84867403285&partnerID=8YFLogxK

U2 - 10.1016/j.coviro.2012.06.010

DO - 10.1016/j.coviro.2012.06.010

M3 - Review article

C2 - 22819020

AN - SCOPUS:84867403285

VL - 2

SP - 556

EP - 560

JO - Current Opinion in Virology

JF - Current Opinion in Virology

SN - 1879-6257

IS - 5

ER -