Dopamine Is Differentially Encoded by D2 Receptors in Striatal Subregions

Michel Engeln, Megan E. Fox, Mary Kay Lobo

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations

Abstract

Striatal dopamine signaling is differentially regulated along the dorso-ventral axis, but how these differences are encoded by dopamine receptors is unknown. In this issue of Neuron, Marcott et al. (2018) show that dopamine activates D2 receptors in regionally distinct ways and dissect the underlying mechanisms behind striatal D2 heterogeneity. Striatal dopamine signaling is differentially regulated along the dorso-ventral axis, but how these differences are encoded by dopamine receptors is unknown. In this issue of Neuron, Marcott et al. (2018) show that dopamine activates D2 receptors in regionally distinct ways and dissect the underlying mechanisms behind striatal D2 heterogeneity.

Original languageEnglish (US)
Pages (from-to)459-461
Number of pages3
JournalNeuron
Volume98
Issue number3
DOIs
StatePublished - May 2 2018

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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