Draft genome sequences of six Escherichia coli isolates from the stepwise model of emergence of Escherichia coli O157:H7

L. V. Rump, E. A. Strain, G. Cao, M. W. Allard, M. Fischer, E. W. Brown, N. Gonzalez-Escalona

Research output: Contribution to journalComment/debatepeer-review

14 Scopus citations

Abstract

Enterohemorrhagic Escherichia coli (EHEC) of serotype O157:H7 has been implicated in food-borne illnesses worldwide. An evolutionary model was proposed in which the highly pathogenic EHEC O157:H7 serotype arose from its ancestor, enteropathogenic E. coli (EPEC) O55:H7 (sorbitol fermenting [SOR+] and +-glucuronidase positive [GUD+]), through sequential gain of virulence, phenotypic traits, and serotype change. Here we report six draft genomes of strains belonging to this evolutionary model: two EPEC O55:H7 (SOR+ GUD+) strains, two nonmotile EHEC O157:H+ strains (SOR+ GUD+) containing plasmid pSFO157, one EHEC O157:H7 (SOR+ GUD+) strain, and one O157:H7 strain containing plasmid pSFO157 (SOR+ GUD+).

Original languageEnglish (US)
Pages (from-to)2058-2059
Number of pages2
JournalJournal of bacteriology
Volume193
Issue number8
DOIs
StatePublished - Apr 2011

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology

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